Twelve Holstein bull calves (6 to 8 wk of age) were used to determine the influence of supplemental dietary Cr on ACTH, cortisol, and immune responses of calves experimentally inoculated with bovine herpesvirus-1 (BHV-1). Calves supplemented with Cr received 3 mg Cr/d (Chromium, n = 6) of a high-Cr-yeast product. Following 53 d of treatment, all calves were fitted with jugular catheters, and bl...

We classify the ODEs that correspond to elliptic CR-manifolds with maximal isotropy. It follows that the dimension of the isotropy group of an elliptic CR-manifold can be only 10 (for the quadric), 4 (for the listed examples) or less. This is in contrast with the situation of hyperbolic CR-manifolds, where the dimension can be 10 (for the quadric), 6 or 5 (for semi-quadrics) or less than 4. We ...

PURPOSE To quantitatively characterize the longitudinal dose exposure-response [urinary N-telopeptide normalized to urinary creatinine (uNTx/Cr) suppression] relationship for denosumab in patients with bone metastases from solid tumors. EXPERIMENTAL DESIGN Data from 373 patients who received denosumab as single or multiple subcutaneous doses ranging from 30 to 180 mg (or 0.01 to 3 mg/kg) admi...

Hill's Conjecture states that the crossing number $\text{cr}(K_n)$ of complete graph $K_n$ in plane (equivalently, sphere) is $\frac{1}{4}\lfloor\frac{n}{2}\rfloor\lfloor\frac{n-1}{2}\rfloor\lfloor\frac{n-2}{2}\rfloor\lfloor\frac{n-3}{2}\rfloor=n^4/64 + O(n^3)$. Moon proved expected crossings a spherical drawing which points are randomly distributed and joined by geodesics precisely $n^4/64+O(n...

Insulin resistance leads to the inability of insulin to control the utilization and storage of glucose. It is associated initially with elevated levels of circulating insulin followed by glucose intolerance which may progress to type 2 diabetes, hyperlipidaemia, hypertension, obesity and cardiovascular diseases. While the causes of these diseases are multifactorial, one nutrient that is associa...

The TiCp/Cu master alloy was prepared via thermal explosion reaction. Afterwards, the nano-sized TiCp/Cu master alloy was dispersed by electromagnetic stirring casting into the melting Cu-Cr-Zr alloys to fabricate the nano-sized TiCp-reinforced Cu-Cr-Zr composites. Results show that nano-sized TiCp can effectively refine the grain size of Cu-Cr-Zr alloys. The morphologies of grain in Cu-Cr-Zr c...

The aim of the present study was to evaluate the effect of different levels of calorie restriction (CR) on liver and muscle mitochondrial oxidant production and antioxidant enzymes activity in adult rats. Male Sprague Dawley rats (n=28) were subjected to 25-75% CR for 15 days. H2O2 production was decreased in muscle mitochondria of 25-50% CR group. H2O2 production decreased in liver mitochondri...

OBJECTIVE Increasing an individual's level of cognitive reserve (CR) has been suggested as a nonpharmacological approach to reducing the risk for Alzheimer's disease. We examined changes in CR in older adults participating over 4 years in the Tasmanian Healthy Brain Project. METHOD A sample of 459 healthy older adults between 50 and 79 years of age underwent a comprehensive annual assessment ...