Patient Selection Criteria Coverage eligibility for genetic testing for BRCA1 and BRCA2 mutations in cancer-affected individuals will be considered when ANY of the following criteria are met:  Individual from a family with a known BRCA1/BRCA2 mutation  Personal history of breast cancer and ≥1 of the following: o Diagnosed age ≤45 years o 2 primary breast cancers when 1st breast cancer diagnos...

The optimal clinical care of burn blisters has not been determined. The effects of burn blister fluid and control serum on epidermal cell proliferation and differentiation were determined. Both burn blister fluid and serum decreased the cell responses necessary for healing of the burn wound by approximately 40%. The degree of suppression varied from 81% to 28% dependency on the specific burn bl...

Burn injuries in both developed and developing countries cause long-term disability, mortality, and socio-economic costs that are imposed on patients, families, and societies. This study was carried out to investigate the epidemiology, outcome, and cost of hospitalization of 388 burn patients admitted to the Imam Khomeini Hospital Burn Center in Kermanshah, Iran, between 21 March 2011 and 20 Ma...

background advances in the care of burn injuries have resulted from the efforts of regional patient-based specialist teams at burn care centers. objectives we conducted this study to assess the four-year epidemiology of burn injuries in rasht, iran. materials and methods in this cross-sectional study, medical records of 2274 burn patients, treated at velayat hospital from january 2007 to decemb...

BACKGROUND Burns are an important health problem in our country and in the world. In our study, we aimed to epidemiologically analyze the patients who were hospitalized in a burn unit that serves 3 million individuals in Central Anatolia. METHODS Records of 457 patients who had been hospitalized in the burn unit during the period 2008-2010 were analyzed retrospectively. Patients were assessed...

Background: Minoxidil has been reported to inhibit in vitro fibroblast proliferation and lysyl hydroxylase activity, a key enzyme in collagen biosynthesis. These in-vitro effects proposed minoxidil to be a potential antifibrotic agent. The present study aimed to investigate the effects of minoxidil gel on wound healing procedure in a second-degree burn model in rats.  Materials and methods: Wis...