The kinetics of hydrogen evolution reaction (HER) was studied in 1M NaOH at various temperatures (298 to 358 K) on Ni-P-C (composite electrodes. The electrochemical efficiency of the electrodes has been evaluated on the basis of electrochemical data obtained from the steady-state polarization Tafel curves, electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV) in 1M NaOH solut...

Inhibitor docking studies have implicated a conserved glutamate residue (Glu-348) as a general base in the synthetase active site of the enzyme asparagine synthetase B from Escherichia coli (AS-B). We now report steady-state kinetic, isotope transfer, and positional isotope exchange experiments for a series of site-directed AS-B mutants in which Glu-348 is substituted by conservative amino acid...

Deep UBVRI-CCD Johnson photometry for 123 stars in the densest region of IC348 open cluster were obtained during three observational runscolour and colour-magnitude diagrams allowed us to classify 114 stars as members of the cluster and to connrm a large presence of pre-main sequence stars. Individual reddening values were computed for the brightest members. The structure and sub-clustering wer...

OBJECTIVE To examine the use of the Medical Outcomes Study short form 36-item (SF-36) health status measure in older patients receiving health care; to explore the influence of age and physical and cognitive status on response to and completion of the SF-36 questionnaire. DESIGN Prospective observational study. SETTINGS Hospital and ambulatory patients aged 65 years and over in the medical ...

A major productivity hurdle for parallel programming is the presence of data races. Data races can lead to all kinds of harmful program behaviors, including determinism violations and corrupted memory. However, runtime overheads of current dynamic data race detectors are still prohibitively large (often incurring slowdowns of 10× or more) for use in mainstream software development. In this pape...

dioxide on bronchoconstriction after pulmonary artery occlusion. Am J Physiol214: 772-775, 1968 33. Severinghaus JW, Stupfel MJ: Alveolar dead space as an index of distribution of blood flow in pulmonary capillaries. J Appl Physiol 10:335-348, 1957 34. Severinghaus JW, Swenson EW, Finley TN, Lategola MT, Williams J: Unilateral hypoventilation produced in dogs by occluding one pulmonary artery. ...

BACKGROUND Cardiac myosin heavy chain-α (Myhc), an intracellular protein expressed in the cardiomyocytes, has been identified as a major autoantigen in cardiac autoimmunity. In our studies with Myhc334-352-induced experimental autoimmune myocarditis in A/J mice (H-2a), we discovered that Myhc334-352, supposedly a CD4 T cell epitope, also induced antigen-specific CD8 T cells that transfer diseas...

BACKGROUND The integrase inhibitor elvitegravir (EVG) has been co-formulated with the CYP3A4 inhibitor cobicistat (COBI), emtricitabine (FTC), and tenofovir disoproxil fumarate (TDF) in a single tablet given once daily. We compared the efficacy and safety of EVG/COBI/FTC/TDF with standard of care-co-formulated efavirenz (EFV)/FTC/TDF-as initial treatment for HIV infection. METHODS In this pha...

BACKGROUND There is mounting evidence that current replacement regimens fail to restore health-related subjective health status fully in patients with adrenal insufficiency (AI). Here we evaluated the subjective health status in primary and secondary AI and the effect of concomitant disease. METHODS In a cross-sectional study, all AI patients registered with the University Hospital Wuerzburg ...