Ascidians and vertebrates belong to the Phylum Chordata and both have dorsal tubular central nervous systems. The structure of the ascidian neural tube is extremely simple, containing less than 400 cells, among which less than 100 cells are neurons. Recent studies suggest that, despite its simple organization, the mechanisms patterning the ascidian neural tube are similar to those of the more c...

Revised selection mechanisms to medicine now include an adjunct admission test known as the HPAT. Stakeholder acceptability is a key issue. General Practitioners (GPs) represent an important stakeholder group. A questionnaire was administered to a regional sample of GPs evaluating their knowledge of the new selection system, views on acceptability, performance on sample HPAT questions and perce...

141 questionnaires were posted to GPs randomly selected in the Mid-West. 103 responses were received. 32 GPs (31%) strongly agreed and 65 GPs (63%) agreed that antibiotics are over used in general practice. 35 GPs (34%) felt under pressure to prescribe an antibiotic at least once a day. 41 GPs (40%) agreed that delayed prescriptions are a safe prescribing strategy. 53 GPs (51%) agreed that dela...

The American College of Medical Informatics (ACMI) periodically hosts a debate at the American Medical Informatics Association (AMIA) fall symposium on a timely topic in biomedical informatics. In 2014 a panel of ACMI fellows debated the following proposition: "The lack of interaction and collaboration between health IT vendors and academic clinical informatics units is stifling innovation and ...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Garncarczyk A, Adamczyk K, Lubczyńska Wcisło-Dziadecka D, Antończak P, Jakubowska M. Structure of children’s skin and rules for its care – what’s new? Children’s structure. Pediatria Polska - Polish Journal Paediatrics. 2021;96(4):258-262. doi:10.5114/polp.2021.112400. APA Garncarczyk, A., Adamczyk, K.,...

*Corresponding author: Mailing address: Environment and Public Health Inspection Division, Health, Social Welfare and Environmental Administration Department, Nagaoka Regional Promotion Bureau, Niigata Prefecture, 2711-1 Kawasaki-Machi, Nagaoka-Shi, Niigata 940-0861, Japan. Tel: +81-258-33-4939, Fax: +81-258-33-4933, E-mail: [email protected]. lg.jp Laboratory and Epidemiology Commun...

1 Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA and 2 Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA * Corresponding author. Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Bldg 76-353F, Cambridge, MA 02139, USA. Tel.: þ 1 617 258 894...

Shwachman-Diamond syndrome (SDS) is a rare hereditary disorder characterized by pancreatic exocrine insufficiency, bone marrow dysfunction and skeletal changes. Recently, the cause of SDS was identified as mutations of Shwachman-Bodian-Diamond syndrome gene (SBDS) and most mutations are caused by gene conversion between SBDS and its highly homologous pseudogene. Clinical variations especially i...

PURPOSE Fms-like tyrosine kinase 3 (FLT3) encodes a receptor tyrosine kinase (RTK) for which activating mutations have been identified in a proportion of acute myelogenous leukemia (AML) patients and associated with poor clinical prognosis. Given the relevance of FLT3 mutations in AML, we investigated the activity of CHIR-258, an orally active, multitargeted small molecule, with potent activity...

Günther et al . report that their control experiment using randomized magnetic field gradient sequences disagreed with findings we had reported linear gradients. However, show measurements in our laboratory are consistent both methods.