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a topical o/w cream containing tretinoin microspheres was prepared. gelatin microspheres of tretinoin were prepared using coacervation method. these microspheres contained about 50% w/w tretinoin. the particle size range of microspheres was between 90-150 m m. in vitro drug release from microspheres and a cream formulation was studied. it was shown that drug release from microspheres followed h...

In this study, we investigated the synthesis of nano-size iron particle using a borohydride reduction of ferric ion in the presence of solvent containing carbonyl groups. When we varied the contents of solvent, there is a corresponding variation of synthesis and iron form. Each sample of synthesized iron particles was characterized by transmission electron microscope (TEM) and powder X-ray diff...

his study was carried out to determine the importance of type 2 Diabetes mellitus as a risk factor for osteoporosis in postmenopausal women. Materials and Methods: This study was conducted in 2004 on 40 diabetic and 40 healthy postmenopausal women attending the endocrine clinics in Zanjan. These two groups were matched in terms of age, length of their menopausal period and body mass index. Seru...

Chance, B. & Conrad, H. (1959). J. biol. Chem. 234, 1568. Chance, B. & Hagihara, B. (1961). Proc. 5th int. Congr. Biochem., Mo8cow, Symp. no. 5. Chance, B. & Hollunger, G. (1960). Nature, Lond., 185, 666. Chance, B. & Williams, G. R. (1955). Advanc. Enzymol. 17, 65. Chappell, J. B. (1961 a). In Biological Structure and Function, vol. 2, p. 71. Ed. by Goodwin, T. W. & Lindberg, 0. London: Academ...

BODE, W. & SCHWAGER, P. (1975). J. MoL Biol. 98, 693717. CHAMBERS, J. L. & STROUD, R. M. (1977). Acta Cryst. B33, 1824-1837. COOLEY, J. W. & TUKEY, J. W. (1965). Math. Comput. 19, 297-301. CRUICKSHANK, O. W. J. (1949). Acta Cryst. 2, 65-82. CUTFIELD, J. F., DODSON, E. J., DODSON, G. G., HODGKIN, D. C., ISAACS, N. W., SAKABE, K. & SAKABE, N. (1975). Acta Cryst. A31, S21. DEISENHOFER, J. & STEIGE...

Human Pim1 kinase is a serine/threonine protein kinase that plays important biological roles in cell survival, apoptosis, proliferation, and differentiation. Moreover, Pim1 is up-regulated in various hematopoietic malignancies and solid tumors. Thus, Pim1 is an attractive target for cancer therapeutics, and there has been growing interest in developing small molecule inhibitors for Pim1. Here, ...

A topical o/w cream containing tretinoin microspheres was prepared. Gelatin microspheres of tretinoin were prepared using coacervation method. These microspheres contained about 50% w/w tretinoin. The particle size range of microspheres was between 90-150 m m. In vitro drug release from microspheres and a cream formulation was studied. It was shown that drug release from microspheres followed H...

The present paper evaluates the technical and economical feasibility of converting wet chemical scrubbers to biotrickling filters for H2S control at the Orange County Sanitation District (OCSD), California. Results of 8 months of continuous operation of a biotrickling filter treating 16,000 m3 h–1 of foul air are analyzed. The reactor was operated at a gas contact time of 1.6 to 2.2 seconds rea...