نتایج جستجو برای: 222 and 187 tonsha
تعداد نتایج: 16829975 فیلتر نتایج به سال:
MicroRNAs (miRNAs/miRs) play crucial roles in cancer development and progression. The purposes of this study were to investigate the role of miR-187 in osteosarcoma and clarify the regulation of MAPK12 by miR-187. Quantitative polymerase chain reaction was used to examine miR-187 expression in osteosarcoma tissues and cell lines. The clinicopathological significance of miR-187 downregulation wa...
MiR-222 in glioma can regulate cell cycle progression and apoptosis. However, the relationship between miR-222 and Wnt/β-catenin signaling pathway in glioma remains unknown. Here, we found that the Dickkopf-2 gene (DKK2) was a direct target of miR-222 by target prediction analysis and dual luciferase reporter assay. RNA interference silencing of DKK2 proved that miR-222 overexpression led to co...
Aberrantly expressed microRNAs contribute to the initiation and progression of human cancer. MiRNA-187 has been reported in nasopharyngeal, renal, pancreatic, prostate, and esophageal cancer, and acts as a tumor suppressor or oncogene. However, the underlying function of miRNA-187 in cervical cancer remains largely unexplored. In the present study, we demonstrated significantly miRNA-187 down-r...
امروزه استفاده از گیاهان دارویی وجایگزین کردن آنها به جای مواد شیمیایی پر خطر در صنعت آبزی پروری رو به افزایش نهاده است. یکی از دلایل این امر وجود باقیمانده های دارویی در بافت های آبزیان، امکان مقاومت دارویی و عدم تاثیر مناسب این داروها بر آبزیان از یک طرف و وجود اثرات سمی و سرطان زا بر روی اکوسیستم های زنده و انسان ها از طرف دیگر است. همچنین، کاربرد گیاهان دارویی بصورت فرآوری شده مقرون به صرفه...
The objects of this study were to assess the knowledge and attitude toward using personal protective equipment (PPE) among 307 farmers who own rubber wood plantation in Southern Thailand. data collected by questionnaires then descriptive statistics analyzed SPSS program. results showed that 187 male (60.9%) 105 (34.2%) 41-50 years old. 120 (36.5%) graduated from primary education. More than hal...
Two highly homologous microRNAs (miRNAs, miRs), miR-222 and miR-221, act as a cluster in cellular regulation. We have previously reported that miR-221 promoted the growth of human non-small cell lung cancer cell line H460. However, the role of miR-222 in regulating the growth of H460 is unclear. H460 cells were transfected with miR-222 mimics, inhibitors or their negative controls and their eff...
The miR-221/222 cluster has been demonstrated to function as oncomiR in human cancers. miR-221/222 promotes epithelial-to-mesenchymal transition (EMT) and confers tamoxifen resistance in breast cancer. However, the effects and mechanisms by which miR-221/222 regulates breast cancer aggressiveness remain unclear. Here we detected a much higher expression of miR-221/222 in highly invasive basal-l...
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