The 2008–2009 Zimbabwe cholera epidemic resulted in 98,585 reported cases and caused more than 4,000 deaths. In this study, we used a mixed-methods approach that combined primary qualitative data from a 2008 Physicians for Human Rights-led investigation with a systematic review and content analysis of the scientific literature. Our initial investigation included semi-structured interviews of 92...

In the first six months of my PhD I have tried to lay a solid foundation in analysis with background reading as well as looking at problems involving finite elements. I hope that this mainly theoretical approach will enable me to produce rigorous results when studying applied problems. More details are included in Section 1. In January I attended the MAGIC Conference in Manchester, where I pres...

Background Restorative dentists and orthodontists have described severely fluorotic teeth as the most difficult surface for bonding.1,2 The difficulty arises from the composition of the enamel of such teeth, which has an acid-resistant, hypermineralized outer layer. As a result, it is very difficult to mechanically treat the surface with conventional 37% phosphoric acid to allow for effective b...

Like other countries, the economic stimulus package in Japan is including healthcare delivery support. For the health informatics domain, there are two large subsidies proposed. One is to provide “the last one mile” optic fiber network to all hospitals in Japan. We have about 9000 hospitals nationwide, and some very local hospitals only have a slower network infrastructure. The other is to supp...

To the Editor: The nematode Angiostrongylus cantonensis was discovered in pulmonary arteries and hearts of domestic rats in Guangzhou (Canton), China, by Chen in 1935 (1). This parasite has a complex life cycle (2) and causes cerebral angiostrongyliasis after ingestion of infective larvae found in freshwater and terrestrial snails and slugs, paratenic hosts (such as freshwater fi sh, shrimp, fr...

HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau...

The beneficial effects of maggots in the wound healing process have been known for centuries. For the past ten years, maggot debridement therapy (MDT) has been used in clinical practices in Europe and the US for the treatment of various types of severely infected wounds with successful healing results. Several historic documents prove that in ancient times maggots, also known as ‘bio-surgeons’,...

Search-and-score algorithms search for a Bayesian network structure that fits the data best (in some sense). They start with an initial network structure (often a graph without arcs or a complete graph), and then traverse the search space of network structures by in each step either removing an arc, adding an arc, or reversing an arc. Read again the paper by Castello and Kočka [1] for a good ov...

From locomotion to cognition..............................................................................................................1 Table of contents..............................................................................................................................1 1 Summary of results (project period 1. 10. 2008 – 30. 9. 2009)....................................................

HIGHLIGHT Ravi Radhakrishnan et al. Molecular systems biology of ErbB1 signaling: bridging the gap through multiscale modeling and high-performance computing Molecular BioSystems January 2009 Epigenetics, Development, and Human Disease, Breckenridge, CO Angiogenesis and Lymphangiogenesis in Cancer, Big Sky, MT Mobilizing Cellular Immunity for Cancer Therapy, Snowbird, UT The Many Faces of Ubiqu...