BACKGROUND Failure to recruit a sufficient number of eligible subjects in a timely manner represents a major impediment to the success of clinical trials. Physician participation is vital to trial recruitment but is often limited. METHODS After 12 months of traditional recruitment to a clinical trial, we activated our electronic health record (EHR)-based clinical trial alert (CTA) system in s...

Insulin-induced capillary recruitment is considered a significant regulator of overall insulin-stimulated glucose uptake. Insulin’s action to recruit capillaries has been hypothesized to involve insulin-induced changes in vasomotion. Data directly linking vasomotion to capillary perfusion, however, are presently lacking. We therefore investigated whether insulin’s actions on capillary recruitme...

it is firstly proved that the multi-input-single-output (miso) fuzzy systems based on interval-valued $r$- and $s$-implications can approximate any continuous function defined on a compact set to arbitrary accuracy.  a formula to compute the lower upper bounds on the number  of interval-valued fuzzy sets needed to achieve a pre-specified approximation  accuracy for an arbitrary multivariate con...

Interval type-2 fuzzy sets, each of which is characterized by the footprint of uncertainty, are a very useful means to depict the linguistic information in the process of decision making. In this article, we investigate the group decision making problems in which all the linguistic information provided by the decision makers is expressed as interval type-2 fuzzy decision matrices where each of ...

Due to its clear benefits in the management of recurrent Clostridioides difficile infection, faecal microbiota transplantation (FMT) has been advocated by gastroenterological community as a non-postponable procedure be continuously delivered during COVID-19 pandemic.1Ianiro G Mullish BH Kelly CR et al.Screening transplant donors outbreak: suggestions for urgent updates from an international exp...