it has been also reported that that h. pylori infection may be responsible for some endocrine disorders, such as autoimmune thyroid diseases, diabetes mellitus and primary hyperparathyroidism. h. pylori which express cytotoxin-associated gene a (caga) may be more virulent than those that do not. the aim was to evaluate the seroprevalence of anti-h. pylori igg and anti-caga  antibodies in patien...

background: economic evaluation includes evaluation of costs and benefits of screening. one of the economic evaluation methods is cost-effectiveness analysis. the aim of this study was cost-effectiveness analysis of type 2 diabetes screening in shiraz, iran.   methods: the target population of this cross-sectional study consisted of all shiraz population over 30 years old. a total of 171067 per...

background: air pollution has been a serious public health threat worldwide. it has been linked to pulmonary and cardiovascular diseases but is also believed to contribute to air-pollution-mediated cardiometabolic disease such as diabetes. we investigated the relationship between type 2 diabetes mellitus (dm2) and air pollution in densely developed urban settings in south korea, using national ...

results the prevalence of micro and macroalbuminuria was 17.2% and 17.6%, respectively. microalbuminuria was significantly associated with longer diabetes duration, increased fasting plasma glucose, and diastolic blood pressure. it was also found that higher plasma glucose and bun (blood urea nitrogen) were risk factors for macroalbuminuria. conclusions prevalence of both micro- and macroalbumi...

introduction: depression is one of the most prevalent mental disorders in patients with diabetes, which affects on cooperation in implementation of treatment measures, consequences of therapeutic and diabetes complications. is thought, low self-esteem is endangering balance of mental and emotional person and is caused development of depression. this study was performing with goal of comparison ...

background the altered levels of some essential trace elements and antioxidant minerals have been observed in diabetic patients. objectives the aim of the present study was to compare the concentrations of essential trace elements, copper (cu), zinc (zn), and iron (fe) in the serum of patients who have type 2 diabetes mellitus (t2dm) with those of their non-diabetic first-degree relatives (fdr)...

background and objectives: there is convincing evidence that subjects concomitantly affected by type 2 diabetes (t2d) and metabolic syndrome (mes) are at greater risk for cardiovascular disease (cvd). many metabolic derangements in t2d might be attributed to poor vitamin d status. the purpose of this study was to investigate the associations among vitamin d status, mes and glycemic status in su...

background: the transcription factor 7-like 2 gene (tcf7l2) is an element of the wnt signaling pathway. there is lack of evidence if tcf7l2 has a functional role in lipid metabolism and regulation of the components constitutes the metabolic syndrome (metsyn).the aims of this study were to evaluate whether the risk allele of tcf7l2 gene polymorphism is associated with dyslipidemia and metsyn. ma...

background: diabetes is a major cause of death. oxidative stress mainly caused by hyperglycemia is the primary reason of related complications. omega-3 fatty acids are prescribed in diabetes but the effect on antioxidant defense is controversial. this study investigated effects of omega-3 supplementation on antioxidant enzymes activity in type 2 diabetic patients. methods: a randomized, placebo...

background: the homeostasis model assessment of insulin resistance (homa-ir) is a useful model for application at large epidemiologic studies. the aim of this study was to determine the homa cut off values to identify insulin resistance (ir) and metabolic syndrome (ms) in qazvin, central iran. methods: overall, 480 men and 502 women aged 20-72 yr attended in this cross sectional study from sept...