نتایج جستجو برای: 2 b phthalazine 5

تعداد نتایج: 3738419  

Journal: :Acta Crystallographica Section E Structure Reports Online 2008

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Journal: :Journal of Chemistry 2013

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Journal: :Drug metabolism and disposition: the biological fate of chemicals 2013
John T Barr Jeffrey P Jones

The goal of this study was to provide a reasonable assessment of how probe substrate selection may impact the results of in vitro aldehyde oxidase (AO) inhibition experiments. Here, we used a previously studied set of seven known AO inhibitors to probe the inhibition profile of a pharmacologically relevant substrate N-[(2-dimethylamino)ethyl]acridine-4-carboxamide (DACA). DACA oxidation in huma...

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Journal: :Pharmacological reports : PR 2012
Hai-Ling Yu Feng Zhang Ying-Jun Li Guo-Hua Gong Zhe-Shan Quan

BACKGROUND QUAN-0808 (6-(4-chlorophenoxy)-tetrazolo[5,1-a]phthalazine), a new phthalazine tetrazole derivative, was evaluated for the anti-inflammatory and analgesic effects. METHODS Xylene-induced ear edema, carrageenan (Carr)-induced paw edema, and acetic acid-induced capillary permeability hyperactivity in mice were used to assess the anti-inflammatory effect; acetic acid-induced writhing ...

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Journal: :Molecules 2012

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Journal: :Biomedical Research 1996

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Journal: :IUCrData 2016

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Journal: :Chemical and Pharmaceutical Bulletin 1974

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Journal: :Japanese Journal of Pharmacoepidemiology/Yakuzai ekigaku 2018

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Journal: :Acta Crystallographica Section E Structure Reports Online 2011

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