Fungal skin infections are the most common disease worldwide. Superficial mycoses caused by Trichophyton rubrum and T.interdigitale one of leading causes for patients to seek dermatological care. Terbinafine (TRB), acting through squalene epoxidase (SQLE) inhibition, is drug choice curing both species. However, TRB-resistant cases increasing. Between 2013 2021, we examined TRB-sensitivity in 54...

∗ Professor and author of correspondence, Phone: (086) 022-26564242, Fax: (086)022-60204278, Email: [email protected] ABSTRACT The modularity indicates a one-to-one mapping between functional concepts and physical components. It can allow us to generate more product varieties at lower costs. Functional concepts can be described by precise syntactic structures with functional terms. Differen...

Objective(s): Ghrelin is a brain-gut peptide involved in substance and energy metabolism. To confirm the hypothesis that ghrelin might be involved in non-alcoholic fatty liver disease (NAFLD), a rat NAFLD model was established and the changes of ghrelin were explored.Materials and Methods: The rats were divided into control and NAFLD gro...

background: available evidence shows that tetracycline family has cellular and molecular mechanisms to protect neurons and oligodendrocytes by modulating matrix metalloproteinases. we tried to compare the effectiveness of intramuscular and subcutaneous interferon beta-1a (inf-β1a) in combination with oral doxycycline among patient with relapsing remitting multiple sclerosis (rrms) and secondary...

Spitzer Space Observatory IRAC and MIPS photometric observations are presented for 20 white dwarfs with Teff . 20, 000 K and metal-contaminated photospheres. A warm circumstellar disk is detected at GD 16 and likely at PG 1457−086, while the remaining targets fail to reveal mid-infrared excess typical of dust disks, including a number of heavily polluted stars. Extending previous studies, over ...

abstract        background and objective: this study was conducted to evaluate epidemiology of risk factors for hepatitis c virus (hcv) transmission, and determine the association of its genotypes with viral load and response to treatment in patients referred to the infectious disease clinic of khorramabad.         methods: the study included patients infected with hepatitis c referred to the i...

Objective(s): In the present study, C57BL/6 female mice (n=56) were used to explore the neuroprotective effects of riboflavin in motor disability of experimental autoimmune encephalomyelitis (EAE) as a model of multiple sclerosis. Materials and Methods: The animals were assigned into 7 groups: sham-operated 1 (SO1), healthy mice receiving PBS (phosphate buffer saline); sham-operated 2 (SO2), h...

Background: Human platelet antigens (HPAs) are part of platelet GP complexes have the potential to contribute to the autoantibody production. Moreover, these antigens demonstrate different patterns of distribution on different ethnic groups and variation in some types of diseases. This study was objected to determine the incidence of HPA-1 to -5 and -15 polymorphisms in the Iranians suffering f...