http://bmj.com/cgi/content/full/336/7637/184 Updated information and services can be found at: These include: References http://bmj.com/cgi/content/full/336/7637/184#BIBL This article cites 12 articles, 4 of which can be accessed free at: Rapid responses http://bmj.com/cgi/eletter-submit/336/7637/184 You can respond to this article at: http://bmj.com/cgi/content/full/336/7637/184#responses free...

a Department of Radiology, Hôpital Saint Antoine, 184, rue du Faubourg-Saint-Antoine, 75012 Paris, France b Department of Anatomic Pathology, Hôpital Saint Antoine, 184, rue du Faubourg-Saint-Antoine, 75012 Paris, France c Department of Gastroenterology, Hôpital Saint Antoine, 184, rue du Faubourg-Saint-Antoine, 75012 Paris, France d Department of Visceral Surgery, Hôpital Saint Antoine, 184, r...

Methyl-CpG binding protein 1 (MBD1) regulates gene expression via a DNA methylation-mediated epigenetic mechanism. We have previously demonstrated that MBD1 deficiency impairs adult neural stem/progenitor cell (aNSC) differentiation and neurogenesis, but the underlying mechanism was unclear. Here, we show that MBD1 regulates the expression of several microRNAs in aNSCs and, specifically, that m...

Hepatocellular carcinoma (HCC) is one of the most common human malignancies and the third leading cause of cancer mortality worldwide. The development and progression of HCC is a complicated process, involving the deregulation of multiple genes that are essential to cell biological processes. Recently, microRNAs (miRNAs) have been suggested to be closely associated with tumorigenesis. Our study...

MicroRNA-184 suppresses cell growth and survival via targeting c-Myc and Bcl- 2. We recently reported that miR-184 promotes tumor progression in non-small cell lung cancer via targeting CDC25A and c-Myc. We here hypothesized that miR-184 could be down-regulated by E6 oncoprotein to confer cisplatin resistance in NSCLC. Human papillomavirus (HPV) 16-positive lung cancer TL-1 and cervical cancer ...

Student engagement is considered an important predictor of student achievement, but few researchers have attempted to derive a valid and reliable measure of college student engagement in particular courses. In 2 studies, we developed and explored the validity of a measure of student engagement, the Student Course Engagement Questionnaire (SCEQ). Exploratory factor analysis revealed 4 dimensions...

BACKGROUND In recent years, miRNAs have been suggested to play key roles in the formation and development of human glioma. The aim of this study is to investigate the effect and mechanism of miR-184 expression on the malignant behavior of human glioma cells. METHODS The relative quantity of miR-184 was determined in human glioma cell lines, and the expression of hypoxia-inducible factor-1 alp...

PURPOSE The aim of this study was to evaluate the microRNA expression patterns in squamous cell carcinoma (SCC) of the tongue. EXPERIMENTAL DESIGN Expression levels of 156 human mature microRNAs were examined using real-time quantitative PCR (Taq Man MicroRNA Assays; Human Panel) on laser microdissected cells of 4 tongue carcinomas and paired normal tissues. Expression of mature miR-184 was f...