نتایج جستجو برای: 177lu psma

تعداد نتایج: 2383  

2017
R. Bhardwaj A. van der Meer S. K. Das M. de Bruin J. Gascon H. T. Wolterbeek A. G. Denkova P. Serra-Crespo

177Lu has sprung as a promising radionuclide for targeted therapy. The low soft tissue penetration of its β- emission results in very efficient energy deposition in small-size tumours. Because of this, 177Lu is used in the treatment of neuroendocrine tumours and is also clinically approved for prostate cancer therapy. In this work, we report a separation method that achieves the challenging sep...

Objective(s): 99mTc-PSMA SPECT/CT is a cost effective alternative for 68Ga-PSMA PET/CT. The aim of this study was to directly compare these two techniques in patients with prostate cancer. Methods: 28 man with prostate cancer were studied using 99mTc-PSMA SPECT/CT and 68Ga-PSMA PET/CT in a shor...

2017
Johanna Dalmo Johan Spetz Mikael Montelius Britta Langen Yvonne Arvidsson Henrik Johansson Toshima Z. Parris Khalil Helou Bo Wängberg Ola Nilsson Maria Ljungberg Eva Forssell-Aronsson

BACKGROUND 177Lu-[DOTA0, Tyr3]-octreotate (177Lu-octreotate) is used for treatment of patients with somatostatin receptor (SSTR) expressing neuroendocrine tumors. However, complete tumor remission is rarely seen, and optimization of treatment protocols is needed. In vitro studies have shown that irradiation can up-regulate the expression of SSTR1, 2 and 5, and increase 177Lu-octreotate uptake. ...

Journal: :European Journal of Nuclear Medicine and Molecular Imaging 2019

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