The marine medaka, Oryzias dancena is a suitable sample as a laboratory animal because it has a small size and clearly distinguishes between female and male. Data on the growth and maturity of the diploid and triploid sea cucurbit species suitable for laboratory animals are very useful for studying other species. Triploidy was induced in the marine medaka by cold shock treatment (0°C) of fertil...

BACKGROUND The purpose of this study was to determine the optimal endometrial preparation protocol by comparing the clinical outcome of two methods of endometrial preparation in frozen-thawed embryo transfer (FET) cycles, including that is, oral estradiol and 17ß-estradiol transdermal patch. METHODS In this randomized controlled trial, women underwent either conventional IVF or intracytoplasm...

Endogenous estrogens exert an array of biological actions on women, many of which are mediated by the estrogen receptors (ERs) α and ß. Results from our recent studies suggest that the human ERα and ERß systems are differentially activated under different physiological conditions. In non-pregnant young women, the ERα system is preferentially activated over the ERß system, mainly by estrone (E1)...

The jill is a long-day breeder with a constant oestrus without mating. Persistent oestrogen production results in clinical signs of hyperoestrogenism including pancytopenia and death if untreated. As spaying is thought to be related to the development of hyperadrenocorticism, a non-invasive, safe and effective long-term treatment is needed for oestrus suppression in jills. Seven jills in oestru...

BACKGROUND Acne vulgaris (AV) is the commonest skin disorder, whereas soybean isoflavone had been proved as antiandrogen that is it can inhibit the enzyme 3ß-hydroxysteroid dehydrogenase,17ß-hydroxysteroid dehydrogenase and 5α-reductase. The purpose of this study is to prove the advantage of soybean isoflavone as antiandrogen on AV. METHODS this study is a clinical study using randomized pret...

23 This study investigated the relationship over time between the concentrations 24 of two steroids, singly and in combination, in a static exposure system and in the 25 blood of sticklebacks, Gasterosteus aculeatus, held within the exposure system. 26 Groups of sticklebacks were exposed (nominally) to either 1000 ng l 17ß-estradiol 27 (E2), Testosterone (T) or E2 & T in combination at the same...

Cisplatin treatment has an overall 19% response rate in animal models with malignant tumors. Increasing gap junction activity in tumor cells provides the targets to enhance antineoplastic therapies. Previously, a new class of substituted quinolines (PQs) acts as gap junction enhancer, ability to increase the gap junctional intercellular communication, in breast cancer cells. We examined the eff...

OBJECTIVES In most DEHP exposure assessment studies, single spot urine sample was used. It could not compare the exposure level among studies. Therefore, we are going to represent the necessity of selection of proper sampling time of spot urine for assessing the environmental DEHP exposure, and the association urinary DEHP metabolites with steroid hormones. METHODS We collected urine and plas...

Sediments from Holes 994C, 995A, 997A, and 997B have been investigated for “combined” gases (adsorbed gas and that portion of free gas that has not escaped from the pore volume during core recovery and sample collection and storage), solventextractable organic compounds, and microscopically identifiable organic matter. The soluble materials mainly consist of polar compounds. The saturated hydro...

The proximate composition, amino acids and fatty acids composition in the muscle of wild, inshore and offshore cage-cultured large yellow croaker, Pseudosciaena crocea (Richardson, 1846), were determined to identify nutritional differences. Wild fish groups showed highest content of moisture and crude protein, but the lowest lipid content. Offshore cage-cultured fish showed significantly higher...