نتایج جستجو برای: 153sm177lu edtmp

تعداد نتایج: 131  

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004
Neeta Pandit-Taskar Maria Batraki Chaitanya R Divgi

Bone metastasis occurs as a result of a complex pathophysiologic process between host and tumor cells leading to cellular invasion, migration adhesion, and stimulation of osteoclastic and osteoblastic activity. The process is mediated by parathyroid hormones, cytokines, and tumor-derived factors. Several sequelae occur as a result of osseous metastases and resulting bone pain can lead to signif...

Journal: :Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1990
J C Lattimer L A Corwin J Stapleton W A Volkert G J Ehrhardt A R Ketring S K Anderson J Simon W F Goeckeler

Forty dogs with spontaneous skeletal neoplasia were treated with 153Sm-EDTMP (ethylenediaminetetramethylene phosphonic acid). Both primary and metastatic lesions were treated. Two treatment regimes, a single (37 MBq (1.0 mCi)/kg dose or two 37 MBq (1.0 mCi)/kg doses separated by 1 wk) were tested. Response to treatment was varied. Large lesions with minimal tumor bone formation responded poorly...

Journal: :Nanoscale 2014
Ruopeng Zhao Gengtao Fu Tongge Zhou Yu Chen Xiaoshu Zhu Yawen Tang Tianhong Lu

Highly branched noble metal nanostructures are highly attractive for catalytic applications owing to their specific physical and chemical properties. In this work, three-dimensional highly branched palladium tetrapods (Pd-THBTs) have been constructed in the presence of polyvinylpyrrolidone (PVP) through one-step hydrothermal reduction of ethylenediamine-tetramethylene phosphonate-palladium(II) ...

2013
Narjess Ayati Kamran Aryana Amir Jalilian Toktam Hoseinnejad Ali Bahrami Samani Zahra Ayati Farzane Shariati S. Rasoul Zakavi

INTRODUCTION Involvement of the skeleton can cause an excruciating pain in two-thirds of terminal patients with a history of malignancy. Due to several limitations of other therapies, such as analgesics, bisphosphonates, chemotherapy, hormonal therapy and external beam radiotherapy; bone-seeking radiopharmaceuticals have an important role in palliation of pain from bone metastases. Although the...

Journal: :Haematologica 2004
Stefan Knop Bernhard M Dohmen Lothar Kanz Roland Bares Hermann Einsele

Even though high-dose chemotherapy followed by autologous stem cell support has proven superior to conventional treatment, relapse occurs in approximately 75% of patients within five years after autologous transplantation. Initiating salvage treatment after high-dose therapy may be a reasonnable approach with survival time from relapse being more than two years as documented recently. Reported ...

Journal: :Journal of the South African Veterinary Association 1998

Ali Mowlavi, Fatemeh Razghandi Reza Izadi,

Introduction One of the important applications of nuclear physics in medicine is the use of radioactive elements as radiopharmaceuticals. Metastatic bone disease is the most common form of malignant bone tumors. Samarium-153-ethylene diamine tetramethylene phosphonate (153Sm-EDTMP) as a radiopharmaceutical is used for pain palliation. This radiopharmaceutical usually emits beta particles, which...

2013
Samaneh Zolghadri Amir Reza Jalilian Zohreh Naseri Hassan Yousefnia Ali Bahrami-Samani Mohammad Ghannadi-Maragheh Hossein Afarideh

OBJECTIVE(S) In this study, (166)Ho-1,2-propylene di-amino tetra(methy1enephosphonicAcid) ((166)Ho-PDTMP) complex was prepared as a bone palliation agent. MATERIALS AND METHODS The complex was successfully prepared using an in-house synthesized EDTMP ligand and (166)HoCl3. Ho-166 chloride was obtained by thermal neutron irradiation (1 × 1013 n.cm-2.s-1) of natural Ho(NO3)3 samples followed by...

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