Residues of pesticide fumigants and toxic industrial chemicals in freight containers represent a health hazard to employees and consumers, especially since freight containers are sealed for transport and distributed widely throughout the importing countries before being opened for unloading. We investigated 2113 freight containers arriving at the second largest container terminal in Europe, Ham...

We study different variants of the augmented Lagrangian (AL)-based block-triangular preconditioner introduced by the first two authors in [SIAM J. Sci. Comput. 2006; 28: 2095–2113]. The preconditioners are used to accelerate the convergence of the Generalized Minimal Residual method (GMRES) applied to various finite element and Marker-and-Cell discretizations of the Oseen problem in two and thr...

Fever in neutropenia (FN) is the most frequent potentially life threatening complication of chemotherapy for cancer. Prediction of the risk to develop FN during chemotherapy would allow for targeted prophylaxis. This retrospective, single centre cohort study in pediatric patients diagnosed with cancer before 17 years covered two decades, 1993 to 2012. The 583 (73%) of 800 patients diagnosed wit...

Attempts at private aquaculture enterprises resulted in few success stories until 1983, when twenty-six scallops survived a shipment to China and were spawned successfully. From this humble beginning, Chinese bay scallop aquaculture yielded 300,000 metric tons of product in 1998, grown on 7,000 hectares of embayment. The Chinese bay scallop has since been readily available in U.S. markets at a ...

In the course of our chemical screening program for novel metabolites by LC-MS monitoring, we isolated a new aspochracin derivative, JBIR-15 (1), together with aspochracin, from the culture broth of a sponge-derived fungus, Aspergillus sclerotiorum Huber Sp080903f04. The structure of 1 was determined to be N-demethyl aspochracin at the alanyl residue on the basis of extensive NMR and MS analyses.

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I was very honored to receive the University of California, San Francisco, and the International Society of Pharmacometrics Lewis Sheiner lecturer award in May 2013. In the present perspective, I outline the main points of my lecture at the American Conference of Pharmacometrics (slides in Supplementary Material 1). I first emphasize the scientific contributions of Lewis Sheiner as a quantitati...

8-puzzle is typically solved by heuristic search. Real-time heuristic search usually gives better results when searching deeper. But sometimes deeper search leads to worse results than shallower which is a phenomenon called search pathology. In this paper we present the results of our investigation of the causes for pathology in 8-puzzle and some of its variations.