RESULTS: Microcalcifications were detected radiographically in 146 of 361 (40%) cores. If calcifications were present on specimen radiographs, histologic detection of these calcifications was made in 114 of 146 (78%) specimens, and diagnosis was made in 118 of 146 (81%). If calcifications were not present on specimen radiographs, histologic detection was obtamed in 27 of 215 (13%) specimens and...

Neural stem cells (NSCs) have been defined as neural cells with the potential to self-renew and eventually generate all cell types of the nervous system. NSCs serve as an ideal cell type for nervous system repair. In the present study, miR-146 overexpression and predicted target (notch 1) were used to study proliferation and differentiation of mouse NSCs. shRNA were used to demonstrate the func...

One of the most conserved glycosylation sites of neuraminidase (NA) is 146-N-glycan. This site is adjacent to the 150-cavity of NA, which is found within the active site and thought to be a target for rational drug development against the antiviral resistance of influenza. Here, through a total of 2.4 μs molecular dynamics (MD) simulations, we demonstrated that 146-N-glycan can stabilize the co...

The cellular mechanisms of high dose systemic acetylcholine receptor (AChR) T cell epitope, alpha 146--162 peptide-induced tolerance in experimental myasthenia gravis were examined. CD4 cells are the prime target for alpha 146--162 peptide-induced tolerance. The expression of CD69, Fas, and B7.2 molecules on AChR-immune lymphocytes was enhanced within 4--12 h after tolerance induction. A high d...

I N T R O D U C T I O N . . 142 IN VIVO D I G E S T I O N I N SIMPLE-STOMACH A N I M A L S . . 142 S T O M A C H . . . 143 SMALL INTESTINE . . 143 H I N D G U T . . 143 FACTORS I N F L U E N C I N G DIGESTIBILITY I N V I V O . . 144 I N VITRO M E T H O D S FOR E S T I M A T I N G D I G E S T I B I L I T Y . . . 145 D I A L Y S I S CELL METHOD . . 145 Objective . . 145 Principle . . 145 Methods....