© 2008 Weller et al. The Rockefeller University Press $30.00 J. Exp. Med. Vol. 205 No. 6 1331-1342 www.jem.org/cgi/doi/10.1084/jem.20071555 1331 In humans, peripheral blood B cells expressing the CD27 marker and mutated Ig receptors are usually considered to be memory B cells generated in germinal centers (GCs) during immune responses to T-dependent (TD) antigens. In adults, approximately half ...

1Human Genome Centre, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia 2King Fahd Medical Research Center, King Abdulaziz University, P.O. Box 80216, Jeddah 21589, Saudi Arabia 3Laboratorio de Neurofisiologia, Departamento de Fisiologia, Universidade Federal do Parana (UFPR), 81531-980 Curitiba, Brazil 4Department of Biochemistry and Molecular Biolo...

In this work, we propose to succinctly review, in non technical terms, the current mathematical state of brittle fracture first put forth by A. Griffith his seminal work (Philos Trans R Soc Lond CCXXI-A:163–198, 1920), then re-interpreted under label “variational fracture” Francfort and Marigo (J. Mech Phys Solids 46(8):1319–1342, 1998). subsequent works. We will only address sharp theory limit...

Abstract Background The Benishangul-Gumuz region is an important development corridor in Ethiopia. Large-scale projects such as the Great Renaissance Dam, mining and agriculture have entailed huge environmental modifications settlement pattern changes. There no detailed epidemiological information on visceral leishmaniasis (VL) region. Materials methods A cross-sectional study was carried out t...

The 2009 H1N1 influenza pandemic has heightened the interest of clinicians for options in the prevention and management of influenza virus infection in immunocompromised patients. Even before the emergence of the novel 2009 H1N1 strain, influenza disease was a serious complication in patients with hematologic malignancies receiving chemotherapy or undergoing hematopoietic cell transplantation. ...

The role of religion and spirituality in coping with disease and promoting health has been reported from many parts of the World. However, no scientific studies on the use of prayers for health and wellbeing have been reported from Pakistan. A cross-sectional survey, using a self-administered questionnaire, was conducted among 1342 graduate and undergraduate students in the twin cities of Islam...