a series of five-membered heterocyclic rings were synthesized by the reaction between benzoyl chloride and various chlolro-nitro-benzoyl chlorides and semi carbazide to form (c1-c7) compounds and was tested for their anti-inflammatory activity determined by rat-paw-oedema method. all the synthesis compounds have been characterized by 1hnmr, ir and mass spectral data. the compounds were purified...

In the title compound, C(23)H(20)F(3)N(5)O, the piperazine ring adopts a chair conformation. The quinoline ring makes dihedral angles of 56.61 (11), 49.94 (12) and 42.58 (14)° with the piperazine ring, the 1,3,4-oxadiazole ring and the benzene ring, respectively. An intra-molecular C-H⋯O hydrogen bond generates an S(7) ring motif. In the crystal, mol-ecules are linked into infinite chains along...

3 Starting from 2-methyl-4-nitro-imidazole, new 5-(2-methyl- 4-nitro-1-imidazomethyl)-1,3,4-oxadiazole-2-thione () was synthesized and was subjected to Mannich reaction with appropriate amines to yield a new series of 3-substituted aminomethyl-5-(2-methyl-4-nitro-1-imidazomethyl)- 1,3,4-oxadiazole-2-thiones (4a-j). The structure of the title compounds was elucidated by elemental analysis and sp...

IN THE TITLE COMPOUND [SYSTEMATIC NAME: 4-(2,3-dibromo-3-phenyl-propano-yl)-3-phenyl-1,2,3-oxadiazol-3-ylium-5-olate], C(17)H(12)Br(2)N(2)O(3), the oxadiazole ring is essentially planar, with a maximum deviation of 0.001 (3) Å. The central oxadiazole ring makes dihedral angles of 73.3 (2) and 29.0 (2)° with the adjacent and remote phenyl rings, respectively. In the crystal, adjacent mol-ecules ...

In the title complex, C(8)H(7)N(3)O, the C-O [1.369 (2) and 1.364 (3) Å] and C=N [1.285 (3) and 1.289 (3) Å] bond lengths in the oxadiazole ring are each almost identical within systematic errors, although different substituents are attached to the ring. The phenyl ring is inclined to the planar oxadiazole ring [r.m.s. deviation 0.002 Å] by 13.42 (18)°. In the crystal, molecules are linked via ...

In the title compound, C(16)H(14)ClN(3)O(2), the 2,3-dihydro-1,3,4-oxadiazole ring [maximum deviation = 0.030 (1) Å] and the pyridine ring [maximum deviation = 0.012 (1) Å] are inclined slightly to one another, making a dihedral angle of 11.91 (5)°. The chloro-substituted phenyl ring is almost perpendicular to the 2,3-dihydro-1,3,4-oxadiazole and pyridine rings at dihedral angles of 86.86 (5) a...

Disc-shaped liquid crystals designed by introducing oxadiazole functional units into a heterocoronene system were explored in thin-film space-charge limited current (SCLC) devices. They found to exhibit ambipolar semiconducting behavior.

Background: The growing spread of drug resistance in Helicobacter pylori has caused concern. Urease is one the most important enzymes associated with H. activity. Oxadiazoles have a wide range inhibitory activities. aim this study was to investigate new oxadiazole compounds as urease inhibitors pylori. Methods: synthesized were reused ligands previous study, and initial structure optimized by M...

In the last three decades investigations in the field of oxadiazoles have been intensified due to their diverse therapeutic uses. Oxadiazole are well known to have a wide range of therapeutic activities namely anti-inflammatory, analgesic, antipyretic, anticonvulsant, antiparasitic, antimicrobial etc. In this study, we have evaluated the antimicrobial activity of some carboxymethyl derivativ...