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Single-chain antibodies neutralize activity and bind nonoverlapping epitopes of botulinum A neurotoxin. Two phage display epitope libraries were constructed from the 1.3 kb of binding domain cDNA. The minimal epitopes selected against the single-chain Fv-Fc antibodies correspond to conformational epitopes with amino acid residues 1115 to 1223 (S25), 1131 to 1264 (3D12), and 889 to 1294 (C25).
infectious disease. Most of the vaccines available today are injected parenterally, and they are not effective for inducing immunity at mucosal surfaces. In contrast, oral vaccines elicit both mucosal and systemic immune responses and have the advantages of self-administration. However, the oral administration of vaccines has the problem of antigen degradation by gastric acid and proteolytic en...
283 Address correspondence to Petr Janata, Dept. of Psychological and Brain Sciences, 6207 Moore Hall, Dartmouth College, Hanover, NH 03755. (e-mail: [email protected]) ISSN: 0730-7829. Send requests for permission to reprint to Rights and Permissions, University of California Press, 2000 Center St., Ste. 303, Berkeley, CA 94704-1223. Online Detection of Tonal Pop-Out in Modulating Cont...
Numerical investigation of indentation tests on a transversely isotropic elastic material by powerlaw shaped axisymmetric indenters Congrui Jin To cite this article: Congrui Jin (2016) Numerical investigation of indentation tests on a transversely isotropic elastic material by power-law shaped axisymmetric indenters, Journal of Adhesion Science and Technology, 30:11, 1223-1242, DOI: 10.1080/016...
The random transposon mutagenesis system P(junc)-TpaseIS(1223) is composed of plasmids pVI129, expressing IS1223 transposase, and pVI110, a suicide transposon plasmid carrying the P(junc) sequence, the substrate of the IS1223 transposase. This system is particularly efficient in Lactobacillus casei, as more than 10,000 stable, random mutants were routinely obtained via electroporation.
357 Address correspondence to Diana Deutsch, Department of Psychology, University of California, San Diego, La Jolla, CA 92093. (email: [email protected]) ISSN: 0730-7829. Send requests for permission to reprint to Rights and Permissions, University of California Press, 2000 Center St., Ste. 303, Berkeley, CA 94704-1223. Speech Patterns Heard Early in Life Influence Later Perception of the Trit...
347 Address correspondence to Emilios Cambouropoulos, Austrian Research Institute for Artificial Intelligence, Schottengasse 3, A-1010, Vienna, Austria. (e-mail: [email protected]) ISSN: 0730-7829. Send requests for permission to reprint to Rights and Permissions, University of California Press, 2000 Center St., Ste. 303, Berkeley, CA 94704-1223. Melodic Cue Abstraction, Similarity, and C...
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