AIM OF STUDY Adiantum, one of the most widely distributed genera of the family Pteridaceae, is employed in folk medicine worldwide. Adiantum latifolium Lam. has been used in Latin American traditional medicine as anxiolytic, analgesic and antiinflammatory. The present study investigates the antinociceptive and antiinflammatory properties of the methanolic extract of Adiantum latifolium (MEA) in...

This study was designed to investigate the potentially protective effects of Curcuma longa Linn. extract (CLE) on carbon tetrachloride (CCl4)-induced hepatotoxicity in rats. Male Sprague-Dawley rats were pretreated with 50 or 100mg/kg of CLE or 100mg/kg of butylated hydroxytoluene (BHT) for 14 days before CCl4 administration. In addition, the CLE control group was pretreated with 100mg/kg CLE f...

Although changes of cerebral blood flow (CBF) in and around traumatic contusions are well documented, the role of CBF for the delayed death of neuronal cells in the traumatic penumbra ultimately resulting in secondary contusion expansion remains unclear. The aim of the current study was therefore to investigate the relationship between changes of CBF and progressive peri-contusional cell death ...

The purpose of the study was to investigate a possible transgenerational effect of the fungicide vinclozolin on the male reproductive system following oral exposure since this effect was reported by Anway et al. [Anway MD, Cupp AS, Uzumcu M, Skinner MK. Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science 2005;308(5727 (June 3)):1466-9] after intraperitoneal ...

BACKGROUND Gastro-esophageal reflux disease (GERD) has become very common in the past three decades. The reason for this, as well as its exact pathophysiologic mechanisms are yet unknown. In this ecologic study we assessed the relation between water nitrate content and prevalence of GERD in Tehran, Iran. METHODS We determined the prevalence of acid regurgitation, heartburn or any of them occu...

Effect of garlic extracts on MSG induced fibroid in wistar rats was studied. Fifteen rats were randomly assigned into three study groups. The animals in Group 1(the control) received a placebo of 5.0ml distilled water via gastric intubation. The animals in the Groups 2 and 3 were treated with 100mg MSG/kg, or a combination of 100mg MSG/kg + 100mg garlic/kg respectively, in a total volume of 5.0...

Description Charged MTS reagents Positively charged reagent that reacts very rapidly and specifically with cysteine groups. Useful tools for protein (transporters, receptors...) structure and activity studies These reagents would fit inside a cylinder about 0.6nm in diameter and 1nm in length (Akabas . MTSEA UP996180 100mg 500mg 1g 2-Aminoethyl MethaneThioSulfonate Hydrobromide CAS [16599-33-0]...

BACKGROUND There is a considerable body of pre-clinical, epidemiological and randomised data to support the hypothesis that aspirin has the potential to be an effective adjuvant cancer therapy. METHODS Add-Aspirin is a phase III, multi-centre, double-blind, placebo-controlled randomised trial with four parallel cohorts. Patients who have undergone potentially curative treatment for breast (n=...

ETHNOPHARMACOLOGICAL RELEVANCE The Juglans regia L. leaf has been traditionally used for treatment of diabetes mellitus in Iran. But yet, no controlled human study has determined its efficacy in diabetic patients. The present study was designed to investigate the effects of the Juglans regia leaf extract on hyperglycemia and lipid profiles in type II diabetic patients. MATERIALS AND METHOD To...