The production of virulence factors by many pathogenic microorganisms depends on the intercellular communication system called quorum sensing, which involves the production and release of signal molecules known as autoinducers. Based on this, new-therapeutic strategies have emerged for the treatment of a variety of infections, such as the enzymatic degradation of signaling molecules, known as q...

The oxy-myoglobin (Mb-O2) structure was probed by QM/MM (hybrid quantum mechanical/ molecular mechanical) calculations using DFT/MM to elucidate the effect of the heme propionates and the protein matrix on the chemistry of heme Fe-O2 moiety. On this line, we have probed the role of His97 in various protonation states of the heme propionate-6.

In the middle of the breeding season, 16 pony mares (n = 4 per day) were slaughtered on four different days (days 6, 14, 17 and the preovulatory day) of the oestrous cycle, day 0 being the day of the last ovulation. All the ovaries were examined histologically; the number, size and atresia (defined by granulosa cell pyknosis) of all follicles larger than 1 mm in diameter were studied, using a K...

objective: much attention is paid to angiogenesis due to its mutual role in health and disease. therefore, the effect of various chemical and physical agents on inhibition of this process has been recently studied. this study was conducted to investigate the synergic effect of glycyrrhizic acid and electromagnetic field on angiogenesis. materials and methods: in this experimental study, 44 ross...