Cardiac glycosides are group of natural products found to be effective against various cancers. The aim of this study is to propose a binding mode for different conformation of cardiac glycoside analogues to Na, K ATPase pump which is an important target for various cancer cell lines. Quantitative structure activity relationships model were developed with the cytotoxic activity (Expt. IC50) of ...

Instituto de Engenharia Mecânica e Gestão Industrial (INEGI). Faculdade de Engenharia da Universidade do Porto (FEUP). Departamento de Engenharia Mecânica e Gestão Industrial (DEMEGI). Rua Dr. Roberto Frias, s/n – 4200-465 Porto, Portugal. e-mail: {victor.albuquerque, tavares}@fe.up.pt 2 Centro de Investigação e Desenvolvimento em Engenharia Mecânica (CIDEM). Departamento de Engenharia Mecânica...

El Estado de Guanajuato es el principal productor trigo (Triticum aestivum L.) la región Bajío que segunda zona productora este cereal en México. En ciclo otoño-invierno (OI)1998-99 se sembraron 98 072 ha trigo, con una producción 510 894 t, logr´ó gran medida satisfacer demanda regional. Sin embargo, siembran predominantemente variedades gluten débil y poco fuerte (3900 1999-00), cuya por indu...

This paper addresses a path loss prediction and optimization by means of Lee’s model for Jiza town, south of Amman city, Jordan. Data were collected from mobile companies in Jordan in the frequency band of 900, and 1800 MHz. The calibrated Lee’s, Hata, and Egli’s path loss models were compared with respect to the original collected data. It is found that for the 900 MHz Lee’s prediction model h...

Autonomous vehicles use a variety of sensors and machine-learned models to predict the behavior surrounding road users. Most in literature focus on quantitative error metrics like root mean square (RMSE) learn report their models' capabilities. This tends ignore more important behavioral aspect models, raising question whether these really human-like behavior. Thus, we propose analyze output mu...

Canopy metrics from ICESat/GLAS lidar waveforms were applied to estimate stemwood volume for a mixed temperate forest. Gaussian decomposition from product GLA14 was used to infer a ground surface return from within the waveform. The region of the waveform returned from the vegetation was subsequently taken to be between this position and the beginning of the waveform signal. The heights of vege...

The automatic compression strategy proposed by Gergel et al. is a near-optimal lossy compression scheme for a given collection of images whose interimage relationships are unknown. Their algorithm uses the root mean square error (RMSE) as a measure of the similarity between two images, in order to predict the compressibility of the difference image. Gergel et al. found that RMSE performed well ...