To determine the contribution of transsarcolemmal calcium flux to abnormal diastolic function produced by brief periods of flow-limiting ischemia and reperfusion, we evaluated early and late diastolic function during transient coronary occlusion and reperfusion before and during administration of intravenous nifedipine (NIF) (10 +/- 1 microgram/kg/min) in nine preinstrumented conscious dogs. We...

Patient (n) 214 199 500 512 Unstable angina 30% 78% 81% 66% Prior MI 40% 46% 42% 44% Diabetis 20% 17% 14% 19% Procedural success 98% 93% 88% Death 0% 0% 0% 0% Q wave MI 0-5% 1-5% 2% 2% Emergent CABG 0% 1% 1% 3% Angiographic data Reference diameter 3-22mm 3-28 mm 3-25 mm 2-9 mm MLD before procedure 1-05 mm 1-19 mm 1-07 mm 0-81 mm Stenosis before procedure 68% 64% 67% 71% MLD after procedure 2-75...

By using different evaluation strategies, we systemically evaluated the performance of Molecular Mechanics/Generalized Born Surface Area (MM/GBSA) and Molecular Mechanics/Poisson-Boltzmann Surface Area (MM/PBSA) methodologies based on more than 1800 protein-ligand crystal structures in the PDBbind database. The results can be summarized as follows: (1) for the one-protein-family/one-binding-lig...

We present a comparison between the published optical, IR and CO spectroscopic redshifts of 86 (sub-)mm galaxies and their photometric redshifts as derived from long-wavelength (radio–mm–FIR) photometric data. The redshift accuracy measured for 13 sub-mm galaxies with at least one robustlydetermined colour in the radio–mm–FIR regime and additional constraining upper limits is ∆z ≈ 0.30. This ac...

This paper presents an effective design methodology and flow, which is validated through three mmwave/sub-mm-wave amplifiers: including W-band LNA with NF=7dB, W-band PA with PAE >11% and D-band amplifier with gain>20dB. The CMOS based amplifiers can be integrated with III-V materials to form heterogeneous integration, such as COSMOS, to achieve the best performance for various applications.

PURPOSE To longitudinally follow epithelial thickness profile changes after myopic LASIK for 1 year to determine when and how epithelial changes occur and when epithelial stability is reached. METHODS Epithelial thickness was measured with Artemis very high-frequency digital ultrasound (ArcScan Inc) across the central 10-mm corneal diameter in 11 eyes before and 1 day, and 1, 3, 6, and 12 mon...