نتایج جستجو برای: 027
تعداد نتایج: 1772 فیلتر نتایج به سال:
BACKGROUND Clostridium difficile infection ranges from mild to severe prolonged diarrhea with systemic symptoms. Previous studies have assessed the correlation of some disease severity parameters to C. difficile ribotypes. However, certain clinical parameters of interest have not yet been evaluated. AIM We conducted an exploratory study to evaluate the correlation of C. difficile ribotypes to...
The epidemiology of Clostridium difficile infection (CDI) is constantly changing and is influenced by antibiotic usage patterns, healthcare patient environment, and emergence of new strains. Between 1982 and 1991, 4 outbreak periods were noted in 1 hospital in Minnesota, each marked by clusters of specific strains, designated by restriction endonuclease typing (REA) as groups B and K (both type...
was found to be slightly different from other HEVs and included a putative ORF (ORF4) of 552 nt that overlapped with ORF1 (online Technical Appendix Figure). A similar pattern of genome organization was observed for both FRHEVs. Phylogenetic analysis of the complete genomes clearly showed that FRHEV was separated from genotype 1–4 HEVs and clustered with rat HEV (Figure). Similar phylogenetic c...
BACKGROUND AND OBJECTIVE Clostridium difficile NAP1/ribotype 027 is associated with severe disease and high mortality rates. Our aim was to determine the prevalence of NAP1/ribotype 027 among C. difficile isolates in a tertiary care hospital, and review the main clinical data. METHODS We included 106 stool samples from 106 patients. Samples were tested for A&B toxins and were cultured on CCFA...
BACKGROUND An outbreak of Clostridium difficile ribotype 027 infection (CDI) occurred at an university hospital, involving 19 departments. To determine what hospital-associated factors drove the outbreak of this particular strain we performed a case-control study. METHODS Cases (n = 79), diagnosed with CDI due to C. difficile ribotype 027 were matched for age and treating medical specialty to...
Dual-Target Binding Ligands with Modulated Pharmacokinetics for Endoradiotherapy of Prostate Cancer.
Prostate-specific membrane antigen (PSMA)-targeted radiotherapy of prostate cancer (PCa) has emerged recently as a promising approach to the treatment of disseminated disease. A small number of ligands have been evaluated in patients, and although early tumor response is encouraging, relapse rate is high and these compounds localize to the parotid, salivary, and lacrimal glands as well as to th...
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