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013 Introduction Need for accurate psychological assessment in the field of mental health has been important and well recognized for various reasons and one of them is be t te r conceptualization of the patients for correct diagnosis and their management. In the evolution of psychological tests, there are many which have been proving them effective for this purpose. One of such tests is Rorscha...
To gain competitive advantage, firms involve suppliers in New Product Development (NPD). However, uncertainty affects selection of suppliers and associated technologies, and selection outcomes in terms of commitment to one supplier or maintaining flexibility. We report on a case study of collaborative NPD with the aim to develop an energy storage unit. The case involved selection of both techno...
Yeast cells contain an RNA polymerase factor, pi, which is a heat-stable protein with an apparent molecular weight of 12,000. This factor stimulates transcription of calf-thymus, salmon-sperm, yeast-nuclear, and T4-phage DNA. It stimulates transcription by each of the four yeast-nuclear RNA polymerases, by rat-liver RNA polymerases I and II, and by Escherichia coli RNA polymerase. pi-Factor can...
Individuals who are heterozygous for the CCR5-Δ32 mutation provide a natural model to examine the effects of reduced CCR5 expression on human immunodeficiency virus (HIV) persistence. We evaluated the HIV reservoir in 18 CCR5-Δ32 heterozygotes and 54 CCR5 wild-type individuals during suppressive antiretroviral therapy. Cell-associated HIV RNA levels (P=.035), RNA to DNA transcriptional ratios (...
Psoriasis (PsO) is a T cell-mediated autoimmune disease without cure. The major risk-associated PsO susceptibility gene encodes for the human leukocyte antigen C*06:02 (HLA-Cw6). Half of patients carry this allele encoding HLA-I molecule which presents short peptides (together known as immunopeptidome) to CD8 cells, thereby initiating immune responses. It unclear presented by HLA-Cw6 are preval...
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