We investigate the association of MUC1 with castration-resistant prostate cancer (CRPC), bone metastasis, and PC recurrence. MUC1 expression was studied in patient-derived bone metastasis and CRPCs produced by prostate-specific PTEN-/- mice and LNCaP xenografts. Elevations in MUC1 expression occur in CRPC. Among nine patients with hormone-naïve bone metastasis, eight express MUC1 in 61% to 100%...

Figure/ground assignment – determining which part of the visual image is foreground and which background – is a critical step in early visual analysis, upon which much later processing depends. Previous research on the assignment of figure and ground to opposing sides of a contour has almost exclusively involved static geometric factors – such as convexity, symmetry, and size – in non-moving im...

and implement high-performance algorithms to compute the discrete Fourier transform (DFT) [17, 24] and matrix multiplication [14, 15] on shared-memory vector multiprocessors. The significance of the tensor product lies in its ability to model both the computational structures occurring in block-recursive algorithms and the underlying hardware structures, such as the interconnection networks [19...

Approximate Bayesian Computation (abc for short) is a family of computational techniques which offer an almost automated solution in situations where evaluation of the posterior likelihood is computationally prohibitive, or whenever suitable likelihoods are not available. In the present paper, we analyze the procedure from the point of view of k-nearest neighbor theory and explore the statistic...

The aim of the study was analysis of long-term results in patients following different methods of the surgical treatment of iatrogenic bile duct injuries. material and methods. Between January 1990 and March 2005, 138 patients – 37 (26.8%) men and 101 (73.2%) women were operated for IBDI in the Department of Gastrointestinal Surgery, Silesian Medical University in Katowice. The mean age was 52....

Concentrations of OH, and major and trace elements were determined in a suite of mantle-derived megacrysts that represent the crystallization products of a kimberlite-like magma at 5 GPa and 1400---1100 C. OH concentrations, determined by singlecrystal Fourier transform infrared spectroscopy, display the following ranges (ppmw H2O): olivine 54---262, orthopyroxene 215---263, garnet 15---74, cli...

OBJECTIVE To compare the outcomes (auditory threshold and open-set speech perception at 48-month follow-up) of a new near-field monitoring procedure, electrical compound action potential, on positioning the auditory brainstem implant electrode array on the surface of the cochlear nuclei versus the traditional far-field electrical auditory brainstem response. STUDY DESIGN Retrospective study. ...

BACKGROUND AND PURPOSE Intracranial angioplasty and stent placement are used to treat intracranial atherosclerotic disease. The 2 interventions have not been directly compared. MATERIALS AND METHODS This was a single-center, single-operator registry of consecutive, symptomatic subjects receiving treatment (angioplasty, BMS, or WS, chosen based on safety as judged by the operator). After Novem...

BACKGROUND Nipple-sparing mastectomy through an inframammary fold incision (NSM-IMF) with implant-based reconstruction (IBR) is a cosmetically preferable approach to breast cancer treatment in appropriate candidates. However, patients who have undergone prior cosmetic breast surgery (CBS) may be at increased risk for postoperative complications secondary to existing surgical scars. OBJECTIVE ...