نتایج جستجو برای: 004
تعداد نتایج: 6002 فیلتر نتایج به سال:
BACKGROUND Lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia (BPH) mainly depend on alpha1-adrenoreceptors (α1-ADR) stimulation, but a link with oxidative stress (OS) is also involved. D-004, a lipid extract of Roystonea regia fruits, antagonizes ADR-induced responses and produces antioxidant effects. The objective of this study was to investigate whether D-004 p...
Introduction Monosodium urate (MSU) crystal induced interleukin-1 (IL-1b) secretion is a critical pathogenic factor in the development of gout and serves as therapeutic target in these patients. Nevertheless, without co-stimulation by a pro-IL-1ß inducing factor, e.g. lipopolysaccharides (LPS), MSU alone cannot induce IL-1b secretion in vitro. The endogenous Toll-like receptor 4 (TLR-4) agonist...
Methods All FMF, TRAPS, MKD and CAPS patients enrolled in the Eurofever registry until March 2013 were evaluated. For each disease gold standards were considered according to the following criteria: i) clinical validation by centers and disease-principal investigator, ii) confirmative molecular analysis (2 mutations for MEFV with at least one mutation in exon 10, 2 mutations of MVK gene, 1 muta...
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