the ability to maintain and study human tissues in in-vivo environment has proved to be a valuable tool in breast cancer research for several decades. the most widely tissues have been xenografts established human breast cancer cell lines into athymic nude mice. the aim of this study was to provide a new accurate and affordable method for the establishment of breast cancer xenograftin nude mice...

o r g a n i z a t i o n s i n a s u p p l y c h a i n a r e i n d e p e n d e n t e n t i t i e s. a l t h o u g h a c o m p l e t e l y i n t e g r a t e d s o l u t i o n m a y r e s u l t i n o p t i m a l s y s t e m p e r f o r m a n c e, s u p p l y c h a i n m e m b e r s a r e i n t e r e s t e d i n o p t i m i z i n g t h e i r o w n o b j e c t i v e r a t h e r t h a n t h a t o f t...

background and purpose: decreased males’ motivation for entering universities has caused a low male/female ratio in different university majors. in 2005-2006 academic year, enrollment of female students in rafsanjan university of medical sciences reached 83.14%. this tremendous gender imbalance may lead to the development of a mono-sex system for health service providers and will.affect the soc...

multiple sclerosis (ms) and its animal model, experimental autoimmune encephalomyelitis (eae), are inflammatory autoimmune diseases of the central nervous system. chymotrypsin is a serine protease with immunomodulatory effect in the peripheral organs. we previously demonstrated the immunomodulatory effect of chymotrypsin in ameliorating the eae in female lewis rats. however, there are sex-based...

conclusions since the severity of the behavioral symptoms in the 6-ohda-induced model of parkinson disease reflects the degree of the lesion in substantia nigra (sn) dopaminergic neurons, it is suggested that using the combination had neuroprotective effects. the obtained data suggest a synergistic neuroprotective and antiparkinsonian effect for flu, glib and b com. at least, a part of this eff...

conclusions more than behalf of the wound isolates were esbl positive, and the presence of blaveb-1 was determined in less than half of these isolates. fortunately, resistance to imipenem and meropenem was low. results the majority of the wound isolates were resistant to augmentin (90%, n = 80) and cefpodoxime (87.6%, n = 78). however, the majority was susceptible to imipenem and meropenem. fif...

results aβ (1-42) stimulated the production of the proinflammatory cytokines il6, il1β, tnfα, and il18 in both the primary microglia cell culture and the b92 cell line. both the raav-il4 construct and the ril-4 protein were found to inhibit production of the most important aβ (1-42)-induced proinflammatory cytokine mrnas in the two types of cells with different patterns. conclusions it seems th...

s e l e c t i o n o f a p p r o p r i a t e g r o u n d m o t i o n i s a k e y e l e m e n t w i t h i n a n y s e i s m i c a s s e s s m e n t o f s t r u c t u r e s. m a n y m e t h o d o l o g i e s h a v e b e e n d e v e l o p e d i n o r d e r t o s e l e c t a n d s c a l e g r o u n d m o t i o n r e c o r d s f o r t h e p u r p o s e o f r e s p o n s e h i s t o r y a n a l y s i ...

background: mammography is the primary imaging technique for detection and diagnosis of breast cancer; however, the contrast of a mammogram image is often poor, especially for dense and glandular tissues. in these cases the radiologist may miss some diagnostically important microcalcifications. in order to improve diagnosis of cancer correctly, image enhancement technology is often used to enha...

up-regulation of cd4+cd25+cd127low/- regulatory t cells (tregs) is a new target in the treatment of asthma. human bone marrow mesenchymal stem cells can up-regulate cd4+cd25+cd127low/- regulatory t cells in vitro,  meanwhile, heme oxygenase-1 (ho-1) plays an important role in the development and maintenance of cd4+cd25+ regulatory t cells. however the mechanism has not yet been adequately under...