Cu is an essential element for plant growth, but the molecular mechanisms of its distribution and redistribution within the plants are unknown. Here, we report that Yellow stripe-like16 (YSL16) is involved in Cu distribution and redistribution in rice (Oryza sativa). Rice YSL16 was expressed in the roots, leaves, and unelongated nodes at the vegetative growth stage and highly expressed in the u...

Cu is an essential element for plant growth, but the molecular mechanisms of its distribution and redistribution within the plants are unknown. Here, we report that Yellow stripe-like16 (YSL16) is involved in Cu distribution and redistribution in rice (Oryza sativa). Rice YSL16 was expressed in the roots, leaves, and unelongated nodes at the vegetative growth stage and highly expressed in the u...

The amyloid-bprecursor protein (APP), a type I transmembrane protein genetically associated with Alzheimer’s disease, has a complex biology that includes proteolytic processing into potentially toxic fragments, extensive trafficking and multiple, yet poorly-defined functions. We recently proposed that a significant fraction of APP is proteolytically cleaved in the neuronal soma into Nand C-term...

Symptoms—Discuss the likely causes. Show him a diagram or model of the lumbar spine indicating the vertebrae, discs, and nerve roots. Explain that his leg pain is due to irritation of the nerve roots and that effective treatment should alleviate both his back pain and his leg pain. History—When taking a history, be alert to: x Any recent trauma, which may raise the possibility of a fracture x “...

Cybersecurity competitions are getting more attention as a prominent approach of computer security education in the past years. It is vital to look into better ways to engage beginners in the competitions to improve computer security education. This work collected and analyzed the solutions of about 3600 Capture The Flag (CTF) challenges from 160 security competitions in the past three years. T...

The flag curvature is a natural extension of the sectional curvature in Riemannian geometry, and the S-curvature is a non-Riemannian quantity which vanishes for Riemannian metrics. There are (incomplete) nonRiemannian Finsler metrics on an open subset in Rn with negative flag curvature and constant S-curvature. In this paper, we are going to show a global rigidity theorem that every Finsler met...

The objective of this work is to develop an automatic method for estimating glottal opening instants (GOIs) using Hilbert envelope (HE). The GOIs are secondary major excitations after glottal closure instants (GCIs) during the production of voiced speech. The HE is defined as the magnitude of complex time function (CTF) of a given signal. The unipolar property of HE is exploited for picking the...

For many ligands of the TNF family, trimer stability and oligomerization status are crucial determinants of receptor activation. However, for the immunostimulatory ligands CD27L, CD40L, 41BBL, and glucocorticoid-induced TNF receptor ligand (GITRL) detailed information regarding these requirements is lacking. Here, we comprehensively evaluated the effect of trimer stability and oligomerization o...

We have developed a rapid, sensitive, and quantitative 96-well microplate-based nonradioactive immunoprecipitation/kinase assay to evaluate mitogen-activated protein kinase (MAPK) activity. Three quantitative nonradioactive imunoprecipitation/kinase assays of MAPK were demonstrated on a 96-well microplate coated with ANTI-FLAG M2 antibody (ANTI-FLAG M2 plate): (i) the capture of phosphorylated ...