نتایج جستجو برای: کلروپروپامید chlorpropamide
تعداد نتایج: 235 فیلتر نتایج به سال:
Intrahepatic cholestasis and cutaneous bullae associated with glibenclamide therapy are described in a 61-year-old diabetic patient who presented wit hypoglycaemic coma. These features have not previously been reported as side effects of glibenclamide therapy, but intrahepatic cholestasis may occur with chlorpropamide, a similar sulphonylurea agent. The mechanism of this cholestasis is not clea...
The differential diagnosis, which lay between insulinoma, extrapancreatic tumour, hepatic disease, and endocrine disease, was narrowed after investigation to an insulinoma or an extrapancreatic tumour. Normally blood insulin values would have established the diagnosis, but they would have been misleading in this case and could have led to a pancreatectomy. Cases such as this fulfil all the crit...
A 25 year old woman suffering from recurrent attacks of hypoglycaemia underwent a laparotomy for suspected insulinoma. No tumour was found, but histology showed islet cell hyperplasia and nesidioblastosis. Although these changes have been reported as a cause of hypoglycaemia in infants, they are only rarely the cause of hypoglycaemia in adults; in the present case they were found to be the resu...
Abnormality in glucose tolerance appears to correlate with arteriosclerotic disease, even when the abnormality is quite mild. Though there is no evidence for prevention of these vascular problems by correction of the carbohydrate abnormality, it seems reasonable to attempt such a correction in an investigational setting. We have used sulfonylurea (tolbutamide, chlorpropamide) in children and yo...
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