Ocean circulation receives its energy input at basin scales while dissipates microscopic mixing scale. How this is transferred across different lengthscales of paramount importance for understanding the ocean equilibration and variability. Advancement in high-resolution numerical simulations recent years has significantly improved our kinetic (KE) cascades from to kilometer scales, although obs...

Genetic circuits and reaction cascades are of great importance for synthetic biology, biochemistry and bioengineering. An open question is how to maximize the modularity of their design to enable the integration of different reaction networks and to optimize their scalability and flexibility. One option is encapsulation within liposomes, which enables chemical reactions to proceed in well-isola...

Parkinson's disease (PD) is a chronic neurodegenerative condition which has the second largest incidence rate among all other neurodegenerative disorders barring Alzheimer's disease (AD). Currently there is no cure and researchers continue to probe the therapeutic prospect in cell cultures and animal models of PD. Out of several factors contributing to PD prognosis, the role of p38 MAPKs (mitog...

Cascades on random networks are typically analyzed by assuming they map onto percolation processes and then are solved using generating function formulations. This approach assumes that the network is infinite and weakly connected, yet furthermore approximates a dynamic cascading process as a static percolation event. In this paper we propose a dynamic Markov model formulation that assumes a fi...

We summarize research on diversity and trophic interactions under a trophic cascades model that is reframed and expanded from the traditional biomassor abundancebased indirect effects and discuss the response of such ―diversity cascades‖ to climate change and other global change parameters. The studies we summarize encompass dynamic processes in which species richness or evenness in one trophic...