Object-oriented databases store many small objects on disks. Disks perform poorly when reading and writing individual small objects. This thesis presents a new storage management architecture that substantially improves disk performance of a distributed object-oriented database system. The storage architecture is built around a large modified object buffer (MOB) that is stored in primary memory...

BACKGROUND AND PURPOSE High recanalization rates achieved with endovascular procedures are not always followed by the expected clinical improvement. These time-consuming procedures imply a delayed reperfusion despite the capacity of earlier intravascular microcatheter bypass to the ischemic tissue beyond the clot. We aimed to explore the safety and feasibility of MOB beyond the clot. MATERIAL...

Heat-killed (HK) Mycobacterium obuense (NCTC13365) is currently being evaluated in the clinic as an immunotherapeutic agent for cancer treatment. Yet, the molecular underpinnings underlying immunomodulatory properties of HK M. obuense are still largely undefined. To fill this void, we sought to perform immunophenotyping, chemokine/cytokine release analysis and genome-wide characterization of mo...

Large amounts of the greenhouse gas methane (CH(4)) are produced by anaerobic mineralization of organic matter in lakes. In spite of extensive freshwater CH(4) emissions, most of the CH(4) is typically oxidized by methane oxidizing bacteria (MOB) before it can reach the lake surface and be emitted to the atmosphere. In turn, it has been shown that the CH(4)-derived biomass of MOB can provide th...

introduction: chemokines are low molecular weight proteins (8-17kda) with the main role of immune cells recruitment to injured tissues. ip-10/mob-1 is a cxc chemokine and different cell systems in response to external stimulation produce this chemokine. various signaling pathways are used by cell and tissue systems to regulate production of proteins e.g. chemokines. therefore we have investigat...

BACKGROUND Bacillus thuringiensis and Bacillus cereus are two important species in B. cereus group. The intensive study of these strains at the molecular level and construction of genetically modified bacteria requires the development of efficient genetic tools. To insert genes into or delete genes from bacterial chromosomes, marker-less manipulation methods were employed. RESULTS We present ...

SiC/Fe and MoSi2/Ni interfaces are investigated using first principles calculations in order to determine the structure of the interfaces and calculate ideal adhesion energies. As a baseline for comparison, calculations were also performed on the Cr/Fe interface, which shows strong adhesion, even stronger than the intrinsic adhesion of Fe. Both ceramic/metal interfaces show good adhesion. Evide...

We present MOB, a service-oriented scripting language, for programming mobile agents. We argue that combining the service-oriented and mobile agent paradigms provides a very natural model for programming a large class of distributed applications. In MOB, mobile agents in a network simultaneously provide and use services. The service interfaces constitute contracts that bind agents among themsel...