fusarium wilt caused by fusarium oxysporum schltdl. f.sp. phaseoli (fop), is one of the important diseases of the common bean in iran and many of the bean growing countries. incidence of the disease has been reported in tropical and semi-tropical regions of the world. this study was carried out to characterize genetic diversity of f. oxysporum isolates from the common bean by vegetative compati...

Schizosaccharomyces pombe switches its mating type by transposing a copy of unexpressed genes from the respective mat2 or mat3 cassettes to mat1. The donor cassettes are located in a silent domain that is separated from the expressed mat1 cassette by the L region. We monitored the expression of ade6 from sites in the L region and examined the relationship between the expression state at these s...

White-nose syndrome (WNS) of bats has devastated bat populations in eastern North America since its discovery in 2006. WNS, caused by the fungus Pseudogymnoascus destructans, has spread quickly in North America and has become one of the most severe wildlife epidemics of our time. While P. destructans is spreading rapidly in North America, nothing is known about the sexual capacity of this fungu...

Genetically programmed recombination plays an important role in differentiation, antigenic variation, and evolution in many systems. Mating-type switching is an example of programmed recombination, and studies of both the budding yeast [1] and fission yeast [2] have provided a wealth of knowledge on how epigenetic and genetic machineries interact with each other to control this process. Fission...

Coxsackievirus B3 (CVB3) belongs to the genus Enterovirus of family Picornaviridae and can cause acute acinar pancreatitis in adults. However, molecular mechanisms pathogenesis underlying CVB3-induced have remained unclear. In this study, we discovered that CVB3 capsid protein VP1 inhibited pancreatic cell proliferation exerted strong cytopathic effects on HPAC cells. Through yeast two-hybrid, ...

Recent evidence suggests that Paracoccidioides species have the potential to undergo sexual reproduction, although no sexual cycle has been identified either in nature or under laboratory conditions. In the present work we detected low expression levels of the heterothallic MAT loci genes MAT1-1 and MAT1-2, the α-pheromone (PBα) gene, and the α- and a-pheromone receptor (PREB and PREA) genes in...

Acremonium chrysogenum, the fungal producer of the pharmaceutically relevant beta-lactam antibiotic cephalosporin C, is classified as asexual because no direct observation of mating or meiosis has yet been reported. To assess the potential of A. chrysogenum for sexual reproduction, we screened an expressed sequence tag library from A. chrysogenum for the expression of mating type (MAT) genes, w...

Commercial plantations of Eucalyptus species have been established in Malaysia, especially during the past 10 years, with aim sustaining supply wood and timber products for industrial use Malaysia. As part an assessment fungal diseases affecting four regions including Kelantan, Pahang, Sabah, Selangor, stem canker disease was discovered to be a widespread infecting This study aimed identify fun...

Cyclin-dependent kinase-activating kinase (CAK) regulates cell cycle G1 exit, where cells commonly commit either to proliferate or to differentiate. CAK activity in G1 regulation is determined by its assembly factor and targeting subunit, ménage à trois 1 (MAT1). The precise mechanism of how proliferation/differentiation transition is induced from cancer cell G1 arrest remains unknown. We prese...

MAT1 (ménage à trois 1), an assembly factor and targeting subunit of the CDK-dependent kinase (CAK), can regulate the cell cycle, transcription, and DNA repair. This study was intended to investigate the role of MAT1 in the reproductive maturation of black tiger shrimp (Penaeus monodon). In this study, the P. monodon MAT1 (PmMAT1) gene was identified and characterized. The full-length cDNA of P...