نتایج جستجو برای: ژن bh
تعداد نتایج: 19820 فیلتر نتایج به سال:
Mutations in the phenylalanine hydroxylase (PAH) gene result in phenylketonuria (PKU). Tetrahydrobiopterin (BH(4))-responsive hyperphenylalaninemia has been recently described as a variant of PAH deficiency caused by specific mutations in the PAH gene. It has been suggested that BH(4)-responsiveness may be predicted from the corresponding genotypes. Data from BH(4) loading tests indicated an in...
We employ cosmological hydrodynamical simulations to study the growth of massive black holes (BHs) at high redshifts subject to BH merger recoils from gravitational wave emission. As a promising host system of a powerful high-redshift quasar, we select the most massive dark matter halo at z = 6 from the Millennium simulation, and resimulate its formation at much higher resolution including gas ...
UNLABELLED Respiratory motion during PET/CT acquisition can cause misregistration and inaccuracies in calculation of standardized uptake values (SUVs). Our aim was to compare the detection and characterization of thoracic lesions on PET/CT with and without a deep-inspiration protocol. METHODS We studied 15 patients with suspected pulmonary lesions who underwent clinical PET/CT, followed by de...
have been no investigations on the roles of NO and BH 4 in CAPD. Therefore, we measured both NO and BH 4 concentrations in spent dialysates of CAPD patients to investigate the relation between the two. The NO concentration was measured by an NO sensor [6, 12] and BH 4 and BH 2 concentrations were measured fluorometrically by the HPLC-based method [13] . This study protocol was approved by the E...
We present an alternative model for launching relativistic jets in active galactic nuclei (AGN) from an accreting Kerr black hole (BH) by converting the accretion disc energy into jet energy, when the rotational energy of the BH is transferred to the inner disc by closed magnetic field lines which connects the BH to the disc (BH-disc magnetic connection). In this way, the available disc energy ...
Studies of the observed characteristics of black–hole (BH) X–ray binaries can be provide us with valuable information about the process of BH formation. In this paper I address some of the aspects of our current understanding of BH formation in binaries and point out some of the existing problems of current theoretical models. In particular, the measured orbital periods and donor–star propertie...
Introduction: Whole heart coronary MRA is typically performed with navigator gating because of the large data needed to achieve an isotropic spatial resolution on the order of 1-2 mm with extensive anatomic coverage (10-16 cm). Previous studies have shown that whole heart coronary MRA can be performed with either a single [1] or double [2,3] breath-hold (BH) approach using highly-accelerated pa...
Previously we showed that Brown Norway (BN/Mcw) rats are more resistant to myocardial ischemia-reperfusion (I/R) injury than Dahl S (SS/Mcw) rats due to increased nitric oxide (x NO) generation secondary to increased heat shock protein 90 (HSP90) association with endothelial nitric oxide synthase (NOS3). Here we determined whether increased resistance to I/R injury in BN/Mcw hearts is also rela...
NO synthase (NOS) can paradoxically contribute to the production of reactive oxygen species when l-arginine or the cofactor R-tetrahydrobiopterin (BH(4)) becomes limited. The present study examined whether NOS contributes to superoxide production in kidneys of hypertensive Dahl salt-sensitive (SS) rats compared with an inbred consomic control strain (SS-13(BN)) and tested the hypothesis that el...
We present a computational screening study of ternary metal borohydrides for reversible hydrogen storage based on density functional theory. We investigate the stability and decomposition of alloys containing 1 alkali metal atom, Li, Na, or K (M(1)); and 1 alkali, alkaline earth or 3d/4d transition metal atom (M(2)) plus two to five (BH(4))(-) groups, i.e., M(1)M(2)(BH(4))(2-5), using a number ...
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