نتایج جستجو برای: ژن 6s rrna1

تعداد نتایج: 17293  

Journal: :Molecular cancer therapeutics 2013
Guyue Liu Rui Wang Yuetong Wang Pengzhan Li Guisen Zhao Linxiang Zhao Yongkui Jing

Ethacrynic acid, a diuretic, inhibits glutathione S-transferase P1-1 (GSTP1-1) activity and induces cell death in malignant cells at high concentrations. To improve ethacrynic acid activity, ethacrynic acid oxadiazole analogs 6s and 6u were synthesized. Although both compounds have greater antiproliferative effects than ethacrynic acid in human HL-60 cells, 6u has a reduced ability to inhibit G...

Journal: :Acta Crystallographica Section E Structure Reports Online 2006

2011
Sébastien P. Faucher Howard A. Shuman

Legionella pneumophila is a gram-negative bacterial species that is ubiquitous in almost any aqueous environment. It is the agent of Legionnaires' disease, an acute and often under-reported form of pneumonia. In mammals, L. pneumophila replicates inside macrophages within a modified vacuole. Many protein regulators have been identified that control virulence-related properties, including RpoS, ...

2011
Hai Huang Hao Wang Albena Kozekova Carmelo J. Rizzo Michael P. Stone

Michael addition of trans-4-hydroxynonenal (HNE) to deoxyguanosine yields diastereomeric 1,N(2)-dG adducts in DNA. When placed opposite dC in the 5'-CpG-3' sequence, the (6S,8R,11S) diastereomer forms a N(2)-dG:N(2)-dG interstrand cross-link [Wang, H.; Kozekov, I. D.; Harris, T. M.; Rizzo, C. J. J. Am. Chem. Soc.2003, 125, 5687-5700]. We refined its structure in 5'-d(G(1)C(2)T(3)A(4)G(5)C(6)X(7...

Journal: :Chemical & pharmaceutical bulletin 2001
Y Yaoita N Suzuki M Kikuchi

Two new bisabolane-type sesquiterpenoids, (3R,4R,6S)-3,4-epoxybisabola-7(14),10-dien-2-one and (1R,3R,4R,5S,6S)-1-acetoxy-8-angeloyloxy-3,4-epoxy-5-hydroxybisabola-7(14),10-dien-2-one, and a new oplopane-type sesquiterpenoid, 14(R)-hydroxy-7beta-isovaleroyloxyoplop-8(10)-en-2-one, were isolated from Farfarae Flos along with three known compounds. The structures of these compounds were elucidate...

Journal: :Food chemistry 2013
M L Samaniego-Vaesken E Alonso-Aperte G Varela-Moreiras

The Spanish market offers a significant number of folic acid (FA) voluntarily fortified foods. We analysed FA and (6S)-5-methyltetrahydrofolic acid ((6S)-5-CH3-H4PteGlu) content in ready-to-eat cereals (RTEC) (n=68) and cow's milk (n=25) by a previously validated affinity chromatography-HPLC method. Contribution to potential FA intakes for children aged 2-13years, was assessed using food consum...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1975
M D Weingarten A H Lockwood S Y Hwo M W Kirschner

A heat stable protein essentail for microtubule assembly has been isolated. This protein, which we designate tau (tau), is present in association with tubulin purified from porcine brain by repeated cycles of polymerization. Tau is separated from tubulin by ion exchange chromatography on phosphocellulose. In the absence of tau, tubulin exists entirely as a 6S dimer of two polypeptide chains (al...

1997
E. Stambulchik Y. Maron

We investigate the Stark effect for spectral transitions between low-lying levels of atoms and ions. We find that often a strong cancellation of the shifts of the lower and upper levels occurs, resulting in a significant reduction in the shift. For accurate calculations, therefore, one has to account for the influence of highprincipal-quantum-number and continuum levels. As examples, the shifts...

Journal: :Molecular cell 2013
Clemens Grimm Ashwin Chari Jann-Patrick Pelz Jochen Kuper Caroline Kisker Kay Diederichs Holger Stark Hermann Schindelin Utz Fischer

Small nuclear ribonucleoproteins (snRNPs) represent key constituents of major and minor spliceosomes. snRNPs contain a common core, composed of seven Sm proteins bound to snRNA, which forms in a step-wise and factor-mediated reaction. The assembly chaperone pICln initially mediates the formation of an otherwise unstable pentameric Sm protein unit. This so-called 6S complex docks subsequently on...

2004
Eliane Luc-Koenig Mihaela Vatasescu

Photoassociation of ultracold atoms induced by chirped picosecond pulses is analyzed in a nonperturbative treatment by following the wavepackets dynamics on the ground and excited surfaces. The initial state is described by a Boltzmann distribution of continuum scattering states. The chosen example is photoassociation of cesium atoms at temperature T=54 μK from the aΣ u (6s, 6s) continuum to bo...

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