Background: Warfarin has a narrow therapeutic window, interacts with some foods, and requires routine monitoring. Direct oral anticoagulants (DOACs) are able to resolve some of the drawbacks of warfarin. Recently, it has been reported that the incidence of major bleeding in patients with atrial fibrillation who are receiving apixaban is similar to that in patients receiving warfarin. We therefo...

OBJECTIVES We studied the effects of rate and some cardioactive drugs on the atrial surface electrocardiogram (ECG). BACKGROUND In atrioventricular block, atrial surface ECG is unmasked. The effect of rate alone permits detection of the effect of other exogenous stimulations such as drugs in the presence of rate alterations. METHODS High fidelity, high gain ECG leads I, II and III were reco...

To examine the specificity of technetium-99m monoclonal antibody (S12) imaging for identifying activated platelets at interventional injury sites in atherosclerotic rabbit arteries, subgroups of unheparinized rabbits (n =39) underwent serial percutaneous transluminal aortic angioplasty (PTA) procedures (with or without intravascular stent placement) followed by in vivo and then ex vivo gamma ca...

Phosphotransacetylase (Pta), a key enzyme in bacterial metabolism, catalyzes the reversible transfer of an acetyl group from acetyl phosphate to coenzyme A (CoA) to produce acetyl-CoA and Pi. Two classes of Pta have been identified based on the absence (Pta(I)) or presence (Pta(II)) of an N-terminal regulatory domain. Pta(I) has been fairly well studied in bacteria and one genus of archaea; how...

Löfberg, A.-M. 2001. Infrainguinal percutaneous transluminal angioplasty in limbs with severe lower limb ischaemia. Acta Universitatis Upsaliensis. Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1060. 58 pp. Uppsala. ISBN 91-5545079-2 Infrainguinal bypass grafting is an established method in the treatment of patients with femoropopliteal and crural occlusive disea...

OBJECTIVE This study investigates the potential role of intravascular ultrasound (IVUS) in the outcome in patients undergoing percutaneous transluminal angioplasty (PTA) of the superficial femoral artery. MATERIALS Angiographic and the qualitative and quantitative IVUS data obtained at the narrowest site derived from 39 patients before and after PTA were analysed. RESULTS Angiographically t...

PURPOSE We aimed to evaluate the clinical usefulness and outcome of angiosome-oriented percutaneous transluminal angioplasty (IP-PTA) and its clinical outcome for isolated infrapopliteal lesions in diabetic critical limb ischemia. METHODS We retrospectively reviewed 70 patients (82 limbs) with diabetic critical limb ischemia who had localized disease at the level of the infrapopliteal artery....

Percutaneous transluminal angioplasty (PTA) is being extensively applied to treat arteriosclerotic lesions. However, this application has not been widely accepted for the treatment of carotid artery stenosis. Successful attempts to relieve cerebral ischemia from extracranial carotid arterial stenosis by PTA are reported. Twenty-seven patients with arteriosclerotic stenosis, fibromuscular diseas...

purpose: the aim of this study was to compare higher-order aberrations between personalized treatment (pt) versus personalized treatment advanced (pta) photorefractive keratectomy (prk) for myopia and myopic astigmatism. methods: in this clinical trial, 80 eyes of 40 patients who met inclusion criteria were enrolled. they underwent prk using pt or pta algorithm randomly. higher-order aberration...

OBJECTIVES Despite the growing number of instruments for the prospective measurement of post-traumatic amnesia (PTA) after traumatic brain injury, fundamental issues about the natural history of its resolution and methods of examination remain unresolved. The aims of the present study were to: (1) examine the sequence of resolution of disorientation and amnesia, and (2) determine if the method ...