A new monoclinic polymorph of the title compound, C(8)H(12)N(4), in the space group P2(1)/n (Z = 4) is reported. The previously known form was also monoclinic, P2(1)/c (Z = 4), but the unit-cell parameters and crystal packing were different [Shoja & Saba (1993 ▶). Acta Cryst. C49, 354-355]. The hexa-hydro-pyrimidine ring of the title compound adopts a chair conformation with a diequatorial subs...

CPCs are a relatively common finding during the second trimester sonography. when a choroid plexus cyst is identified, the presence of structural malformation and other sonographic markers of aneuploidy should be assessed with a detailed fetal anatomic survey performed by an experienced person. if no other sonographic abnormalities are present, the CPC is considered isolated. given the consider...

introduction: few studies are conducted on the efficacy of antispasmodics in the treatment of functional gastrointestinal disorders in children. we evaluated the effectiveness of a smooth-muscle relaxant (mebeverine) in the treatment of childhood functional abdominal pain (fap).   materials and methods: children (n=115, aged 6-18 years) with fap were randomized to receive mebeverine 135 mg twic...

Silver, Randi B., and Manoocher Soleimani. H1-K1-ATPases: regulation and role in pathophysiological states. Am. J. Physiol. 276 (Renal Physiol. 45): F799–F811, 1999.—Molecular cloning experiments have identified the existence of two H1-K1-ATPases (HKAs), colonic and gastric. Recent functional and molecular studies indicate the presence of both transporters in the kidney, which are presumed to m...

Friedman, Mark I., Ruth B. Harris, Hong Ji, Israel Ramirez, and Michael G. Tordoff. Fatty acid oxidation affects food intake by altering hepatic energy status. Am. J. Physiol. 276 (Regulatory Integrative Comp. Physiol. 45): R1046–R1053, 1999.—Inhibition of fatty acid oxidation stimulates feeding behavior in rats. To determine whether a decrease in hepatic fatty acid oxidation triggers this beha...