In treating Major Depressive Disorder with associated painful physical symptoms (PPS), the effect of duloxetine on PPS has been shown to decompose into a direct effect on PPS and an indirect effect on PPS via depressive symptoms (DS) improvement. To evaluate the changes in relative contributions of the direct and indirect effects over time, we analyzed pooled data from 3 randomized double-blind...

هدف: در قرن 21 رسالت دانشگاه، تربیت نیروی انسانی و نسل آینده‌ای متعهد، مبتکر کارآفرین است بنابراین ایجاد تفکر کارآفرینی ورود به کسب‌ وکار میان دانش‌آموختگان دانشگاهی باعث می‌شود که آنها با بهره‌گیری از استعدادهای بالقوه خود، افرادی خلاق، نوآور شوند خود را باور نمایند. هدف مطالعه حاضر، طراحی الگوی دانشگاه رویکرد سازمانی آموزش عالی بود.طراحی/ روش‌شناسی/ رویکرد: این پژوهش نظر کاربردی-توسعه‌ای، ماه...

Pentosan polysulfate sodium (PPS) was compared with placebo for the symptomatic therapy of interstitial cystitis in a double-blind, multicenter study. A total of 110 patients were enrolled and treated for three months. In this study, overall improvement of greater than 25 percent was reported by 28 percent of the PPS-treated patients and by 13 percent of the placebo-treated patients (p = 0.03)....

Stimuli from different sensory modalities occurring on or close to the body are integrated in a multisensory representation of the space surrounding the body, i.e., peripersonal space (PPS). PPS dynamically modifies depending on experience, e.g., it extends after using a tool to reach far objects. However, the neural mechanism underlying PPS plasticity after tool use is largely unknown. Here we...

Few data are available in the literature regarding the effect of pentosan polysulfate (PPS) on normal and fibrotic rat livers. In addition, the combination of PPS and carbon tetrachloride (CCl4) has not been studied so far. The objective of this study was to assess the effect of PPS on rat livers treated or not with CCl4 for the induction of liver fibrosis. The study consisted of four stages: 1...

Immunohistochemical study of perivascular plaques (PPs) in 7 patients with Alzheimer's disease (AD) and 4 with cerebral amyloid angiopathy (CAA)(CAA with dementia in 3 patients and CAA with massive cerebral hemorrhage in 1 patient) demonstrated that PPs were also a common form of amyloid P (AP) deposits, like SPs and CAAs, in both AD and CAA, and that they had similar immunostaining characteris...

A packet switch with parallel switching planes is a parallel packet switch (PPS). A PPS can scale-up to faster line speeds than can a singleplane switch. It is an open problem to design a PPS that is feasible to implement using existing low-cost hardware components where no component runs faster than line speed. A PPS must be able to internally load balance traffic, have packet delays comparabl...