BACKGROUND Ki67 labeling index (Ki67 LI), the percentage Ki67 immunoreactive cells, is a measure of tumor proliferation, with important clinical relevance in breast cancer, and it is extremely important to standardize its evaluation. AIM To test the efficacy of computer assisted image analysis (CAIA) applied to completely digitized slides and to assess its feasibility in routine practice and ...

Objective: Hemodialysis is one of the most common treatment methods in kidney patients. To do this, repeated insertion needle into vessel necessary. Patients treated with hemodialysis are exposed to stress and pain caused by perforation their arteriovenous fistula about 300 times a year. More than 1/5 patients express this as unbearable. This study aims evaluate effect acupressure at SP6 ST36 a...

results there were significant differences between the groups in subjective labor pain scores (except vas 4) (p < 0.001). the duration of the phase one (3 cm dilatation to full dilatation) and phase two (full dilatation to birth) in the acupressure group was shorter than the control group (phase one, 225 min and 320 min, respectively; phase two, 15 min and 20 min, respectively; both p < 0.001)....

abstract introduction: primary dysmenorrhea is common in women during reproductive age. objective: this study aimed to determine the effect of acupressure on sixth spleen point (sp6) on relief of primary dysmenorrhea. methods: this study is a clinical trial. students with primary dysmenorrheal living in dormitory were studied during three menstrual cycles. pain intensity was measured on the fir...

BACKGROUND The ratio between amygdala:hippocampal (AH) volume has been associated with multiple psychiatric problems, including anxiety and aggression. Yet, little is known about its biological underpinnings. Here, we used a methylome-wide approach to test (a) whether DNA methylation in early life (birth, age 7) prospectively associates with total AH volume ratio in early adulthood, and (b) whe...

Deqi, according to traditional Chinese medicine, is a specific needle sensation during the retention of needles at certain acupoints and is considered to be necessary to produce therapeutic effects from acupuncture. Although some modern researches have showed that Deqi is essential for producing acupuncture analgesia and anesthesia, the data are not enough. It is a paper of a multicenter, rando...

به کمک شبیه ­سازی دینامیک مولکولی می ­توان تحلیل کوتاه مدت در مقیاس زمانی چند ده پیکوثانیه ­ای را برای مواد آسیب دیده­ی تابشی مورد مطالعه قرار داد. بر همین مبنا این ­سازی، تعداد تعادلی عیوب نقطه بین ­نشین و تهی ­جای مختصات مکانی آن­ها آهن- آلفا دست آورده شد. سپس با استفاده از نتایج حاصل شده، مونت کارلوی جنبشی شیء منظور بررسی تأثیر بازپخت آلفای انجام نشان دادند که یکنواخت دیده­ ی تنها خوشه جای ب...

OBJECTIVE To investigate the influence of substance P on gonadotropin release from the pituitary as evaluated according to the final effect, i.e. the ovulation. METHODS Stainless steel tube was implanted into the 3rd cerebral ventricle and substance P (SP), C-terminal hexapeptide of Substance P (SP6-11), Gn-RH and adrenaline were infused on the 3rd day of the cycle (proestrus). The oviducts w...