Increased proportions of naive B cell subset and B cells defined as CD27(neg)CD21(neg)CD38(neg) are frequently found in patients with common variable immunodeficiency (CVID) syndrome. Current methods of polychromatic flow cytometry and PCR-based detection of κ deletion excision circles allow for fine definitions and replication history mapping of infrequent B cell subsets. We have analyzed B ce...

Non-enzymatic glycation (NEG) and enzymatic biochemical processes create crosslinks that modify the extracellular matrix (ECM) and affect the turnover of bone tissue. Because NEG affects turnover and turnover at the local level affects microarchitecture and formation and removal of microdamage, we hypothesized that NEG in cancellous bone is heterogeneous and accounts partly for the contribution...

In present study, an in vitro glycation model comprising both plasma and glucose designed to assess glycation inhibitory potentials of N. sativa seed (NS) extracts. Plasma with several glucose quantities in the presence of NS were incubated for thirty-five days at 37°C. Non-enzymatic glycation (NEG) was quantified by Thiobarbituric acid technique. NEG levels were reduced by NS. Higher NS concen...

So far the contribution of New Economic Geography (NEG) has been mainly positive. Normative analysis and policy implications have lagged behind. The reason is the fear of the consequences of taking too literally the neat structure of the models. Under this respect the somewhat incautious aim of this paper is precisely to take NEG models literally and ask what their exact policy implications are...

Cytomegalovirus (CMV) usually causes lifelong asymptomatic infection, but over time can distort immune profiles. Recent reports describe selective expansion of Vδ2(neg) γδ T cells in healthy and immunocompromised CMV carriers. Having shown previously that virus-specific CD8(+) and CD4(+) T cell responses are increased significantly in elderly CMV carriers, probably driven by chronic stimulation...

The objective was to investigate the effect of various doses and durations of ractopamine hydrochloride (RAC) on pig HCW, cutting yields, and meat quality. Late-finishing pigs (approximately 93 kg) were allotted to 12 treatments 35 d before slaughter. Treatments consisted of negative control (NEG; 13.1% CP, 0.64 TID Lys), positive control (POS; 17.8% CP, 0.94 TID Lys), and 2 RAC doses (5 and 7....