Multiplex reverse transcription polymerase chain reaction (mRT-PCR) has recently emerged as an alternative to cytogenetics. We designed and used simplified mRT-PCR system as a molecular screen for acute leukemia. Fifteen fusion transcripts were included: BCR-ABL1, PML-RARA, ZBTB16-RARA, RUNX1-RUNX1T1, CBFB-MYH11, DEK-NUP214, TCF3-PBX1, ETV6-RUNX1, MLL-AFF1, MLL-MLLT4, MLL-MLLT3, MLL-MLLT10, MLL...

UNLABELLED Malignant rhabdoid tumors (MRT), a pediatric cancer that most frequently appears in the kidney and brain, generally lack SNF5 (SMARCB1/INI1), a subunit of the SWI/SNF chromatin-remodeling complex. Recent studies have established that multiple SWI/SNF complexes exist due to the presence or absence of different complex members. Therefore, the effect of SNF5 loss upon SWI/SNF complex fo...

Parallel space-sharing job scheduling algorithms play an indispensible role in efficient allocation of processors of PC-cluster to the competing jobs to achieve one of the performance objective(s) viz. minimized mean response time (MRT), minimized average bounded slowdown or maximized throughput. Traditional performance modeling and evaluation studies of parallel spacesharing job scheduling alg...

Malignant rhabdoid tumor (MRT), a highly aggressive cancer of young children, displays inactivation or loss of the hSNF5/INI1/SMARCB1 gene, a core subunit of the SWI/SNF chromatin-remodeling complex, in primary tumors and cell lines. We have previously reported that reexpression of hSNF5 in some MRT cell lines causes a G1 arrest via p21(CIP1/WAF1) (p21) mRNA induction in a p53-independent manne...

A combination of solid phase extraction (SPE) columns was used for selective separation of water-soluble arsenic species: arsenite, arsenate, monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA). The SPE columns, namely AnaLig TE-01 (TE-01), AnaLig AN-01 Si (AN-01) and AnaLig As-01 PA (As-01), contain immobilized macrocyclic material as the sorbent and commonly known as molecular recogni...

AIMS Accurate orientation within true three-dimensional (3D) anatomies is essential for the successful radiofrequency (RF) catheter ablation of atrial fibrillation (AF) and atrial macro-re-entrant tachycardia (MRT). In this prospective study, ablation of AF and MRT was performed exclusively using a pre-acquired and integrated computed tomography (CT) image for anatomical 3D orientation without ...