Members of the cysteine- and glycine-rich protein family (CRP1, CRP2, and CRP3) contain two zinc-binding LIM domains, LIM1 (amino-terminal) and LIM2 (carboxyl-terminal), and are implicated in diverse cellular processes linked to differentiation, growth control, and pathogenesis. Here we report the solution structure of full-length recombinant quail CRP2 as determined by multi-dimensional triple...

The expression of specific transcription factors determines the differentiated features of postmitotic neurons. However, the mechanism by which specific molecules determine neuronal cell fate and the extent to which the functions of transcription factors are conserved in evolution are not fully understood. In C. elegans, the cholinergic and peptidergic SMB sensory/inter/motor neurons innervate ...

The effect of a long-acting somatostatin analogue SMS 201.995 (SMS; Sandoz) on basal and gastrin-stimulated growth of 4 human colon cancer lines was studied in vitro and in vivo. Proliferation assay was done with overnight [75Se]selenomethionine uptake after 5 days of incubation. Gastrin concentrations used were 5e-10 M and 1e-7 M. SMS concentrations were from 2e-12 M to 2e-7 M. Cell lines LIM ...

The effect of a long-acting somatostatin analogue SMS 201.995 (SMS; Sandoz) on basal and gastrin-stimulated growth of 4 human colon cancer lines was studied in vitro and in vico. Proliferation assay was done with overnight |75Se|selenomethionine uptake after 5 days of incubation. Gastrin concentrations used were 5e-10 M and le-7 M. SMS concentrations were from 2e-12 M to 2e-7 M. Cell lines LIM ...

The papers [23], [24], [4], [5], [2], [20], [21], [9], [1], [22], [13], [15], [16], [12], [10], [11], [17], [14], [25], [3], [7], [6], [19], and [8] provide the notation and terminology for this paper. For simplicity, we adopt the following convention: X denotes a complex Banach algebra, w, z, z1, z2 denote elements of X, k, l, m, n denote natural numbers, s1, s2, s3, s, s ′ denote sequences of...

We have previously shown that the LIM domains of paxillin operate as the focal adhesion (FA)-targeting motif of this protein. In the current study, we have identified the capacity of paxillin LIM2 and LIM3 to serve as binding sites for, and substrates of serine/threonine kinases. The activities of the LIM2- and LIM3-associated kinases were stimulated after adhesion of CHO.K1 cells to fibronecti...

and Applied Analysis 3 Lemma 2.5. Let {xn}n −1 be a positive solution of 1.1 and limn→∞Pn S. Then S lim supn→∞xn. Proof. Since Pn is a subsequence of xn, it follows that S ≤ lim sup n→∞ xn. 2.6 On the other hand, by xn 1 ≤ Pn for all n ≥ 1, we obtain lim sup n→∞ xn ≤ lim sup n→∞ Pn S. 2.7 The proof is complete. Remark 2.6. Let {xn}n −1 be a positive solution of 1.1 . By Lemma 2.2, we see that i...

The aim of this note is to point out a fallacy in the proof of Theorem 3.1 contained in the recent paper ( Int. J. Contemp. Math. Sci. 5 (2010), 2699-2707) proved in intuitionistic fuzzy metric spaces employing the newly introduced notion of sub-compatible pair of mappings wherein our claim is also substantiated with the aid of an appropriate example. We also rectify the erratic theorem in two ...