p-glycoprotein (p-gp) is a trans-membrane drug efflux pump. several drugs are p-gp substrates. some drugs may affect the activity of p-gp by inhibiting its function, resulting in significant drug-drug interactions (ddis). it is critical to understand which drugs are inhibitors of p-gp so that adverse ddis can be minimized or avoided. this study investigated the effects of gliclazide, metformin,...

The present research was planned to explore the biochemical properties and antioxidant activity of newly developed Pakistani rye variants. For this purpose, four different variants (Gp-1, Gp-2, Gp-3, Gp-4) were procured from forage section Ayub Agriculture Research Institute, Faisalabad. In first phase, each sample milled convert it into powder analyzed for their phytochemical profile. second m...

We describe practical algorithms from computational algebraic number theory, with applications to class field theory. These include basic arithmetic, approximation and uniformizers, discrete logarithms and computation of class fields. All algorithms have been implemented in the Pari/Gp system.

Guaiacol peroxidases (GP) are haem-containing enzymes participating in many physiological processes in plants. The expression pattern of these enzymes is organ-specific and developmentally regulated. Methods: The presence of GP activity in extract samples, prepared from Crocus sativus L. corms that were either dormant or rooting for 3, 6 and 10 days, was investigated. Results: Kinetic studies r...