R. Schnittker1,* and S.D. Marshall2,3 1 Monash Injury Research Institute, Monash University, Building 70, 21 Alliance Lane, Clayton Campus, Clayton, VIC 3800, Australia, 2 Department of Anaesthesia and Perioperative Medicine, Monash University, Melbourne, VIC 3800, Australia, and 3 Monash Simulation Centre, Monash Health, 823-865 Centre Road, East Bentleigh, Melbourne, VIC 3165, Australia *Corr...

Hyperpolarization-activated HCN pacemaker channels are critical for the generation of spontaneous activity and the regulation of excitability in the heart and in many types of neurons. These channels produce both a voltage-dependent current (I(h)) and a voltage-independent current (I(inst) or VIC). In this study, we explored the molecular basis of the voltage-independent current. We found that ...

Vegetative incompatibility in fungi has long been known to reduce the transmission of viruses between individuals, but the barrier to transmission is incomplete. In replicated laboratory assays, we showed conclusively that the transmission of viruses between individuals of the chestnut blight fungus Cryphonectria parasitica is controlled primarily by vegetative incompatibility (vic) genes. By r...

OBJECTIVES To compare the discriminative power of the five-level version of the EuroQol five-dimensional questionnaire (EQ-5D-5L [5L]) and its three-level version (EQ-5D-3L [3L]) in patients with diabetes in Singapore. METHODS A consecutive sample of patients with type 2 diabetes mellitus (T2DM) self-completed the two versions of the EQ-5D in the clinic. The 3L index score was calculated from...

1 Environmental Hydrology and Water Resources Group, Department of Infrastructure Engineering, The University of Melbourne, Melbourne, VIC, Australia, 2 Law School, The University of Melbourne, Melbourne, VIC, Australia, 3 Australian Rivers Institute, Griffith University, Nathan, QLD, Australia, 4 Institute for Water Education, IHE Delft, Delft, Netherlands, 5 The Murray Darling Freshwater Rese...

1 Oral Health Cooperative Research Centre, Melbourne Dental School, University of Melbourne, Parkville, VIC, Australia, 2 Bio21 Institute, University of Melbourne, Parkville, VIC, Australia, 3 Faculty of Chemistry and Mineralogy, Institute of Bioanalytical Chemistry, Universität Leipzig, Leipzig, Germany, 4 Center for Biotechnology and Biomedicine, Universität Leipzig, Leipzig, Germany, 5 Exper...

1 Monash Online-Psychology Education Division (MO-PED), Faculty of Medicine, Nursing and Health Sciences, School of Psychological Sciences, Monash University, Clayton, VIC, Australia, 2 Melbourne Centre for the Study of Higher Education, The University of Melbourne, Melbourne, VIC, Australia, 3 Faculty of Medicine, Nursing and Health Sciences, School of Psychological Sciences, Monash Institute ...

Department of Environment and Primary Industries, AgriBio, 5 Ring Road, Bundoora, VIC, 3083, Australia Dairy Futures Cooperative Research Centre (CRC), AgriBio, 5 Ring Road, Bundoora, VIC, 3083, Australia Melbourne School of Land and Environment, The University of Melbourne, Parkville, VIC, 3010, Australia Department of Animal and Poultry Science, University of Guelph, Guelph, Ontario, N1G 2W1,...

Fabiano Baroni* and Alberto Mazzoni 1 School of Psychological Sciences, Monash University, Clayton, VIC, Australia 2 NeuroEngineering Laboratory, Department of Electrical and Electronic Engineering, University of Melbourne, Parkville, VIC, Australia 3 Centre for Neural Engineering, University of Melbourne, Carlton, VIC, Australia 4 The BioRobotics Institute, Scuola Superiore Sant’Anna, Ponteder...

Vasoactive intestinal contractor (VIC)/endothelin-2 (ET-2) is a 21 amino acid intestinal peptide characterized as a potent vasoactive and intestinal smooth muscle-contracting compound. To investigate the physiological roles of VIC/ET-2 further, we characterized the specificity of VIC gene expression relative to that of other members of the endothelin (ET) ligand-receptor system in adult mouse t...