Voltage clamp experiments were performed to analyse the influence of the slow inward current (isi) on the repolarisation process in frog atrium. MnCl2 was used as isi blocker. The action potential was prolonged by depolarising pulses applied during the plateau. This was an expected result considering that, at positive potentials the time constant for isi inactivation increases. This effect was ...

An electrophysiological approach was used to study a distributed random electrical neuromuscular stimulation (ENMS) scheme in which a probability density is assigned to the inter-stimulus intervals (ISI) of the stimuli. One of the objectives of using ENMS techniques in the study of skeletal muscles is to obtain information about the electrical, physiological, and mechanical properties of muscle...

A perfect integrate-and-fire model driven by colored noise is studied by means of the interspike interval (ISI) density and the serial correlation coefficient. Exact and approximate expressions for these functions are derived for weak dichotomous or Gaussian noise, respectively. It is shown that correlations in the input result in positive correlations in the ISI sequence and in a reduction of ...

In this paper a closed-form approximated expression is proposed for the Intersymbol Interference (ISI) as a function of time valid during the entire stages of the non-blind adaptive deconvolution process and is suitable for the noisy, real and two independent quadrature carrier input case. The obtained expression is applicable for type of channels where the resulting ISI as a function of time c...

BACKGROUND A variety of objective and subjective methods exist to assess insomnia. The Insomnia Severity Index (ISI) was developed to provide a brief self-report instrument useful to assess people's perception of sleep complaints. The ISI was developed in English, and has been translated into several languages including German. Surprisingly, the psychometric properties of the German version hav...

The purpose of this paper is to offer a method to help to objectively compare quality of publication in biomedical journals in different disciplines with varying ISI Impact Factors (IF). Three methods--the number of journals per ISI Journal Citation Report discipline category/10, the IF/10, and the log (IF+1)/10--were used to calculate an article score. The distribution of article scores were c...

Numerical investigations have been made of responses of a Hodgkin-Huxley (HH) neuron to spike-train inputs whose interspike interval (ISI) is modulated by deterministic, semi-deterministic (chaotic), and stochastic signals. As deterministic one, we adopt inputs with the time-independent ISI and with time-dependent ISI modulated by sinusoidal signal. The Rössler and Lorentz models are adopted fo...

OBJECTIVES Use of a local calibrator has been recommended for standardization of the international normalized ratio (INR) and international sensitivity index (ISI). We investigated the performance of two commercial local calibrators for warfarin monitoring and determined the significance of liver-specific INR. METHODS ISI values were determined using the World Health Organization (WHO) method...