CANADIAN GERIATRICS JOURNAL, VOLUME 19, ISSUE 4, DECEMBER 2016 The editorial board of the Canadian Geriatrics Journal would like to present the last issue of 2016, addressing a wide variety of geriatric and gerontological topics. Dr. David Hogan and Dr. Montero-Odasso(1) call on the Canadian Geriatrics Society to develop a Falls and Fractures Special Interest Group, which is an attempt to syste...

Affiliations: European Institute for Systems Biology and Medicine, CNRS-ENS-UCBL, Université de Lyon, Lyon, France. APHP, Hôpital Bichat, Service de Pneumologie A, Centre de Compétences des Maladies Pulmonaires Rares, Paris, France. Université Paris Diderot, Sorbonne Paris Cité, INSERM Unité 1152, Paris, France. Airway Disease Section, National Heart and Lung Institute, Imperial College London,...

Objective: Our recent studies have demonstrated voltagegated KCNQ channels (KCNQ1-KCNQ5) as key regulators of detrusor smooth muscle (DSM) function. Despite emerging developments, the physiological role of individual KCNQ channel subtypes remains less clear. Here, we utilized the novel compound ML-213, a potent activator of KCNQ2, KCNQ4, and KCNQ5 channels, to elucidate their physiological role...

The BEDT-TFF molecules with monovalent anions or iodine complexes form conducting salts, which are less onedimensional (1D) than the compounds of the TTF-TCNQ or (TMTSF)2X families. For example in the c~and 13 modifications of (BEDTTTF)213, abreviated ct, [3 (ET)213, the side by side interaction of the ET molecules is comparable to the face to face interaction [1]. The room tempe-rature conduct...

Sex differences have been found in the anatomy of brains of a wide variety of vertebrates including humans. Common lore tells us that sex differences in the brain cause sex differences in behavior. This review entertains the possibility that sex differences in the brain may also do the exact opposite. Specifically, sex differences may allow males and females to display remarkably similar behavi...

Environment matting is a powerful technique for modelling the complex light-transport properties of real-world optically active elements: transparent, refractive and reflective objects. Zongker et al [1999] and Chuang et al [2000] show how environment mattes can be computed for real objects under carefully controlled laboratory conditions. However, for many objects of interest, such calibration...