AIMS Early ethanol consumption could be a risk factor for young brain integrity and its maturation, and also for the development of addictive behaviors in adulthood. Neuronal nitric oxide synthase (nNOS) expressing neurons are specifically located in the subgranular layer (SGL) of dentate gyrus and may be relevant for hippocampal neurogenesis. The focus of this work is aimed to determine local ...

The cellular localization of the nerve growth factor-like immunoreactivity (NGF-LIR) has been studied in the intact adult rat brain at the level of the hippocampus and the septum. Immunolabelling for NGF combined with counterstaining with cresyl violet and double immunostaining technique, which allowed simultaneous localization of NGF-LIR and that of astroglial marker -GFAP, were used. The data...

This paper considers the problem of simple linear regression with intervalcensored data. That is, n pairs of intervals are observed instead of the n pairs of precise values for the two variables (dependent and independent). Each of these intervals is closed but possibly unbounded, and contains the corresponding (unobserved) value of the dependent or independent variable. The goal of the regress...

Using Northern blotting with a human genomic DNA probe for the pro-opiomelanocortin (POMC) gene, we have shown specific mRNA in normal human peripheral mononuclear cells (PBMC); the presence of specific mRNA was also observed in a T lymphocyte cell line derived from a patient with lymphoma. We then demonstrated that PBMC translate the message into protein. Thus, using a radioimmunoassay with an...

New moderate-resolution mid-infrared spectroscopy at 10 μm of 27 infrared galaxies is presented. The galaxies have been chosen from three 60 μm selected and one 12 μm selected complete flux-limited catalogs of galaxies; 17 of these sources have LIR(8– 1000μm) ≥ 5 × 10 L⊙. A high-resolution spectrum of the source Arp 299B1 is also presented. Combining these new results with previously published ...

Using Northern blotting with a human genomic DNA probe for the pro-opiomelanocortin (POMC) gene, we have shown specific mRNA in normal human peripheral mononuclear cells (PBMC); the presence of specific mRNA was also observed in a T lymphocyte cell line derived from a patient with lymphoma. We then demonstrated that PBMC translate the message into protein. Thus, using a radioimmunoassay with an...

Macroautophagy/autophagy has been shown to mediate the selective lysosomal degradation of pathogenic bacteria and viruses (xenophagy), and to contribute to the activation of innate and adaptative immune responses. Autophagy can serve as an antiviral defense mechanism but also as a proviral process during infection. Atg8-family proteins play a central role in the autophagy process due to their a...

We report the first systematic study of the submillimeter water vapor rotational emission lines in infrared (IR) galaxies based on the Fourier Transform Spectrometer (FTS) data of Herschel SPIRE. Among the 176 galaxies with publicly available FTS data, 45 have at least one H2O emission line detected. The H2O line luminosities range from ∼ 1× 105 L⊙ to ∼ 5× 10L⊙ while the total IR luminosities (...

Selective autophagy contributes to cellular homeostasis by delivering harmful material into the lysosomal system for degradation via vesicular intermediates referred to as autophagosomes. The cytoplasm-to-vacuole targeting pathway is a variant of selective autophagy in Saccharomyces cerevisiae during which hydrolases such as prApe1 are transported into the vacuole. In general, selectivity is ac...

We have investigated optical properties of 4248 infrared galaxies (IRGs) by positionally matching data from the Infrared Astronomical Satellite (IRAS) and the Sloan Digital Sky Survey Data Release 3 (SDSS DR3). Due to the large sky area coverage of both surveys, we have obtained an opportunity to study an unprecedentedly large number of 4248 infrared galaxies spanning four orders of infrared lu...