A–1 Without loss of generality, assume d1 ≤ d2 ≤ ·· · ≤ d12. If d2 i+2 < d 2 i + d 2 i+1 for some i ≤ 10, then di,di+1,di+2 are the side lengths of an acute triangle, since in this case d2 i < d 2 i+1+d 2 i+2 and d 2 i+1 < d 2 i +d 2 i+2 as well. Thus we may assume d2 i+2 ≥ d2 i + d2 i+1 for all i. But then by induction, d2 i ≥ Fid 1 for all i, where Fi is the i-th Fibonacci number (with F1 = F...

The present investigation was carried out with 20 genotypes of pea (Pisum sativum L.) at Horticulture Research Centre (HRC) SVPUAT, Meerut, U.P, during 2021-22 to identify the nature and magnitude genetic divergence among based on phenotypical traits using multivariate analysis. experiment laid down in randomized block design (RBD) three replications. has ten observations five randomly selected...

Bu çalışmada döndürücüye ait kanat sayısı, sarım açısı ve uzunluğu ile yakıt giriş çapının yanma odasındaki türbülanslı akış yapısı, verimi emisyon değerleri üzerine etkisi araştırılmıştır. Referans alınan döndürücü sayısı (n), (L), (θ) çapı (D2) sırası 10, 40 mm, 45°, 19.5 mm’dir. Kanat (6,8,10,12,14), (0.5L, L, 1.5L, 2L), (30°, 60°, 75°, 90°, 120°) için (0.5 D2, 1.5 2 D2) parametrik değerler ...

We report a structure-based biological approach to identify the proton-transfer pathway in photosystem II. First, molecular dynamics (MD) simulations were conducted analyze H-bond network that may serve as Grotthuss-like proton conduit. MD show D1-Asp61, acceptor of H2O at Mn4CaO5 cluster (W1), forms an via one water molecule with D1-Glu65 but not D2-Glu312. Then, D1-Glu65, D2-Glu312, and adjac...

Long-term inhibition of D2 dopamine receptors using classic D2 dopamine receptor antagonists such as haloperidol often causes a compensatory up-regulation of the D2 dopamine receptors. We investigated whether the long-term inhibition of D2 dopamine receptors using an eukaryotic expression vector housing a cDNA sequence encoding an antisense RNA directed to the D2 dopamine receptor transcript (D...

In this report, we investigated whether the D5 dopamine receptor, given its structural and sequence homology with the D1 receptor, could interact with the D2 receptor to mediate a calcium signal similar to the G(q/11) protein-linked phospholipase C-mediated calcium signal resulting from the coactivation of D1 and D2 dopamine receptors within D1-D2 receptor heterooligomers. Fluorescent resonance...

We investigated the mechanism by which T4 regulates its activation to T3 by the type 2 iodothyronine deiodinase (D2). D2 is a short- lived (t1/2 50 min), 31-kDa endoplasmic reticulum (ER) integral membrane selenoenzyme that generates intracellular T3. Inhibition of the ubiquitin (Ub) activating enzyme, E1, or MG132, a proteasome blocker, inhibits both the basal and substrate-induced acceleratio...

The type 2 iodothyronine deiodinase (D2) is an integral membrane ER-resident selenoenzyme that activates the pro-hormone thyroxine (T4) and supplies most of the 3,5,3'-triiodothyronine (T3) that is essential for brain development. D2 is inactivated by selective conjugation to ubiquitin, a process accelerated by T4 catalysis and essential for the maintenance of T3 homeostasis. A yeast two-hybrid...

BACKGROUND Vitamin D (D) supplements are indispensable for its world-wide deficiency. Controversy continues on ergocalciferol (D2) and cholecalciferol (D3) relative potency as well as on dosing-schedule and sex role in raising 25-hydroxy D (25(OH)D) level, the best indicator of D status. METHODS We randomized 279 adults to daily D2, D3, D2/D3, or placebo; 2-weekly D2 or D3; or 4-weekly D2 or ...

Mushrooms exposed to sunlight or UV radiation are an excellent source of dietary vitamin D2 because they contain high concentrations of the vitamin D precursor, provitamin D2. When mushrooms are exposed to UV radiation, provitamin D2 is converted to previtamin D2. Once formed, previtamin D2 rapidly isomerizes to vitamin D2 in a similar manner that previtamin D3 isomerizes to vitamin D3 in human...