background: dermatophytes are the main cause of human superficial mycosis that is still a public health problem especially in tropical countries such as iran. objective: the aim of this study was determining the antifungal effect of hypercom perforatum essential oil. methods: the minimum inhibitory concentration (mic) and minimum fungicidal concentration (mfc) for the essential oil of the plant...

In this study, plant oils of Hypericum perforatum, Sesamum indicum, Nigella sative were investigated for their in vitro antibacterial activity against Vibrio anguillarum and Lactococcus garvieae. Antibacterial activity was found to show with oil of Nigella sative. It was determined formed on the diameter of inhibition (inhibition zone: 18 mm) of the oil against Vibrio anguillarum and Lactococcu...

Adhyperforin is a novel constituent of Hypericum perforatum L., but its antidepressant-like activity remains unclear. To explore that, several well-validated animal models of depression as well as neurotransmitter reuptake and transporter binding assays were conducted. The results showed adhyperforin could reduce the immobility time of mice in the forced swimming test and tail suspension assay,...

Background: Dermatophytes are the main cause of human superficial mycosis that is still a public health problem especially in tropical countries such as Iran. Objective: The aim of this study was determining the antifungal effect of Hypercom perforatum essential oil. Methods: The minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) for the essential oil of the pl...

Hypericum perforatum is an herb whose use dates back centuries. Extracts of the plant are available as over-the-counter treatment options for depression. The genus consists approximately 500 species, most which have not yet been studied. Antimicrobial resistance has reached alarming levels, indicating a post-antibiotic era many become less effective. For this reason, nine species were studied t...

Hypericum perforatum (HP), better known as St. John's Wort, has been used clinically for centuries. Modern usage is still quite diverse and includes kidney and lung ailments, insomnia and depression. Standardised extracts of HP are widely used in the treatment of psychovegetative disorders and especially for mild forms of depression. Several bioactive constituents of this plant may play importa...

The effect of the gene dosage on the expression of rRNAs was studied in Hypericum perforatum. The methylation levels of rDNA were analysed using the isoschizomers MspI and HpaII and eleven additional methylation-sensitive enzymes. No differences in rDNA methylation were observed between diploids and tetraploids at an early ontogenetic stage.